Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.49 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12436889 | 0.93 | OPRM1 (0.54) | OPRM1OPRL1CYP26B1CYP26A1RXRA | |
| SCHEMBL12858074 | 0.91 | ACHE (0.46) | OPRM1OPRL1CYP26B1CYP26A1RXRA | |
| SCHEMBL27009310 | 0.89 | KDM1A (0.47) | OPRM1OPRL1CA4MAPTKMT2A | |
| SCHEMBL18288047 | 0.86 | CA1 (0.48) | OPRM1OPRL1CYP26B1CYP26A1RXRA | |
| SCHEMBL12857985 | 0.85 | ACHE (0.43) | OPRM1OPRL1CYP26B1CYP26A1RXRA | |
| SCHEMBL12957015 | 0.83 | OPRM1 (0.40) | OPRM1OPRL1CYP26B1CYP26A1RXRA | |
| SCHEMBL12857816 | 0.80 | ACHE (0.56) | OPRM1OPRL1CYP26B1CYP26A1RXRA | |
| SCHEMBL12857675 | 0.80 | ACHE (0.56) | OPRM1OPRL1CYP26B1CYP26A1RXRA | |
| SCHEMBL11616948 | 0.76 | CYP26A1 (0.39) | OPRM1OPRL1CYP26B1CYP26A1RXRA | |
| SCHEMBL27009309 | 0.76 | CYP26B1 (0.40) | OPRM1OPRL1CYP26B1CYP26A1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963563-B2 | Reversible derivatization of poly (aryl ether ketones) | CYTEC TECHNOLOGY CORP. (US) | 2018-05-08 | — | — | US | disclosed |
| US-20180030227-A1 | REVERSIBLE DERIVATIZATION OF POLY (ARYL ETHER KETONES) | CYTEC TECHNOLOGY CORP. (US) | 2018-02-01 | — | — | US | disclosed |
| US-9828478-B2 | Reversible derivatization of poly (aryl ether ketones) | CYTEC TECHNOLOGY CORP. (US) | 2017-11-28 | — | — | US | disclosed |
| US-20160075840-A1 | Reversible Derivatization of Poly (Aryl Ether Ketones) | CYTEC TECHNOLOGY CORP. (US) | 2016-03-17 | — | — | US | disclosed |
| US-20110040045-A1 | REVERSIBLE DERIVATIZATION OF POLY (ARYL ETHER KETONES) | CYTEC TECHNOLOGY CORP. | 2011-02-17 | — | — | US | disclosed |