Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | F9 | P00740 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711042 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1ADRB2HSP90AA1ESR2 | |
| SCHEMBL10118778 | 0.81 | HSD17B10 (0.43) | ALDH1A1ADORA3ADORA2AADORA1HSD17B10 | |
| SCHEMBL10120015 | 0.77 | DGAT2 (0.37) | SMN1; SMN2ALDH1A1ADORA3ADORA2AADORA1 | |
| SCHEMBL10147093 | 0.77 | DDAH1 (0.43) | SMN1; SMN2HTTADORA3ADORA2AADORA1 | |
| SCHEMBL30490138 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1ADRB2HSP90AA1ESR2 | |
| SCHEMBL6300137 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1ADRB2HSP90AA1ESR2 | |
| SCHEMBL7914435 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1ADRB2HSP90AA1ESR2 | |
| SCHEMBL19485892 | 0.73 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1ADRB2HSP90AA1ESR2 | |
| SCHEMBL6299123 | 0.72 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1ADRB2HSP90AA1ESR2 | |
| SCHEMBL18237706 | 0.72 | MAPKAPK2 (0.39) | SMN1; SMN2ALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189129-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2011-08-04 | — | — | US | disclosed |
| WO-2007045096-A1 | OLIGOHETEROAROMATIC LUMINISCENT ASSEMBLIES AS HIGH-AFFINITY DNA SEQUENCE-DIRECTED LIGANDS | UNIVERSITY OF SASKATCHEWAN (CA) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110189129-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, HCCS, NSUN2 | SMN1; SMN2 4341/4885ALDH1A1 901/4885ADRB2 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.