SCHEMBL12437151

SCHEMBL12437151

CCOC(=S)Cc1ccc(OC)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
HTT P42858 1/20 0.49
PKM P14618 1/20 0.49
KMT2A Q03164 2/20 0.47
GLA P06280 1/20 0.47
HPGD P15428 2/20 0.46
GAA P10253 2/20 0.46
MAPT P10636 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18235712 0.82 MEN1 (0.47) ALDH1A1KMT2AHPGDGAATDP1
SCHEMBL11270504 0.82 F2RL1 (0.53) ALDH1A1PKMKMT2AGLAMAPT
SCHEMBL11537463 0.80 MAPT (0.43) KMT2AMAPTSMN1; SMN2MEN1NPC1
SCHEMBL11265080 0.79 MAPT (0.48) ALDH1A1KMT2AGAAMAPTSMN1; SMN2
SCHEMBL11539975 0.79 KMT2A (0.41) ALDH1A1HTTKMT2AGLAMAPT
SCHEMBL9742546 0.79 CYP3A4 (0.47) ALDH1A1HTTKMT2AGAAMAPT
SCHEMBL3251246 0.79 ALDH1A1 (0.44) ALDH1A1KMT2ASMN1; SMN2MEN1LMNA
Hydrochloric Acid SCHEMBL8865281 0.78 CYP3A4 (0.46) ALDH1A1HTTKMT2AGAAMAPT
SCHEMBL924496 0.78 KMT2A (0.63) ALDH1A1HTTKMT2AGLAGAA
Hydrochloric Acid SCHEMBL9125038 0.76 IDO1 (0.49) ALDH1A1HTTKMT2AGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110790641-B Method for producing compound having oxydifluoromethylene skeleton 大金工业株式会社 2023-02-28 CN disclosed
EP-3053875-B1 FLUORINATING AGENT DAIKIN IND LTD (JP) 2022-09-28 EP disclosed
CN-106132915-B Method for producing compound having oxydifluoromethylene skeleton 大金工业株式会社 2020-03-31 CN disclosed
CN-110790641-A Method for producing compound having oxydifluoromethylene skeleton 大金工业株式会社 2020-02-14 CN disclosed
US-10479681-B2 Fluorinating agent DAIKIN INDUSTRIES, LTD. (JP) 2019-11-19 US disclosed
US-20190152779-A1 FLUORINATING AGENT DAIKIN INDUSTRIES, LTD. (JP) 2019-05-23 US disclosed
US-10233080-B2 Fluorinating agent DAIKIN INDUSTRIES, LTD. (JP) 2019-03-19 US disclosed
US-20160332877-A1 FLUORINATING AGENT DAIKIN INDUSTRIES, LTD. (JP) 2016-11-17 US disclosed
EP-3053875-A1 FLUORINATING AGENT Daikin Industries, Ltd. (JP) 2016-08-10 EP disclosed
EP-1304316-B1 PROCESSES FOR THE PRODUCTION OF FLUORINATED ORGANIC COMPOUNDS AND FLUORINATING AGENTS DAIKIN IND LTD (JP) 2011-08-10 EP disclosed
US-7311890-B2 Process for the production of fluorinated organic compounds and fluorinating agents DAIKIN INDUSTRIES, LTD. (JP) 2007-12-25 US disclosed
US-7311890-B2 Process for the production of fluorinated organic compounds and fluorinating agents DAIKIN INDUSTRIES, LTD. (JP) 2007-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10479681-B2 Fluorinating agent AFF2, AFF4, AFF1 ALDH1A1 2167/4885HTT 1107/4885PKM 4451/4885
US-20160332877-A1 FLUORINATING AGENT AFF2, AFF4, AFF1 ALDH1A1 2167/4885HTT 1107/4885PKM 4451/4885
US-10233080-B2 Fluorinating agent AFF2, AFF4, AFF1 ALDH1A1 2167/4885HTT 1107/4885PKM 4451/4885
US-20190152779-A1 FLUORINATING AGENT AFF2, AFF4, AFF1 ALDH1A1 2167/4885HTT 1107/4885PKM 4451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.