Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537463 | 0.92 | MAPT (0.43) | MAPTL3MBTL1NPC1RAB9APOLB | |
| SCHEMBL11540438 | 0.90 | MAPT (0.42) | MAPTL3MBTL1NPC1RAB9APOLB | |
| SCHEMBL18235712 | 0.84 | MEN1 (0.47) | L3MBTL1NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL9742546 | 0.81 | CYP3A4 (0.47) | MAPTNPC1RAB9AALDH1A1GAA | |
| SCHEMBL11539975 | 0.81 | KMT2A (0.41) | MAPTL3MBTL1POLBALDH1A1LMNA | |
| SCHEMBL3251246 | 0.80 | ALDH1A1 (0.44) | L3MBTL1POLBALDH1A1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL8865281 | 0.79 | CYP3A4 (0.46) | MAPTNPC1RAB9APOLBALDH1A1 | |
| SCHEMBL12437151 | 0.79 | ALDH1A1 (0.49) | MAPTNPC1ALDH1A1GAALMNA | |
| SCHEMBL11534926 | 0.77 | MAPT (0.48) | MAPTL3MBTL1NPC1RAB9APOLB | |
| SCHEMBL703931 | 0.77 | MAPT (0.72) | MAPTL3MBTL1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514621-B | Method for constructing C-C bond at ortho-position of aryl by metal-catalyzed sulfur ylide and aryl sulfur/selenoacetic acid ester rearrangement reaction | 四川大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-116514621-A | Method for constructing C-C bond at ortho-position of aryl by metal-catalyzed sulfur ylide and aryl sulfur/selenoacetic acid ester rearrangement reaction | 四川大学 | 2023-08-01 | — | — | CN | disclosed |
| US-4337263-A | 1-Aryl-4-γ-arylsulphonyl-3-aminopropoxy-1H-pyrazoles and their use as hypolipemiant and hypocholesterolemiant agents | LABORATOIRE ROGER BELLON (FR) | 1982-06-29 | — | — | US | disclosed |