Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265080 | 0.92 | MAPT (0.48) | MAPTPPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL11540438 | 0.83 | MAPT (0.42) | MAPTCYP1A2CYP3A4MAOAMAOB | |
| SCHEMBL12437151 | 0.80 | ALDH1A1 (0.49) | MAPTKMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL11539696 | 0.78 | LTA4H (0.47) | MAPTPPARALTA4HEPHX2MAOA | |
| SCHEMBL11537202 | 0.78 | LTA4H (0.50) | MAPTPPARALTA4HEPHX2MAOA | |
| SCHEMBL18235712 | 0.77 | MEN1 (0.47) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL11541552 | 0.76 | PPARA (0.43) | MAPTPPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL10345457 | 0.75 | RAB9A (0.50) | MAPTPPARAL3MBTL1KMT2AMEN1 | |
| SCHEMBL9742546 | 0.74 | CYP3A4 (0.47) | MAPTCYP1A2CYP3A4TSHRMAOA | |
| SCHEMBL11539975 | 0.74 | KMT2A (0.41) | MAPTCYP1A2L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156011-A | TREATMENT OF CARDIOVASCULAR DISORDERS | SOCIETE ANONYME DITE: LABORATOIRE L. LAFON (FR) | 1979-05-22 | — | — | US | disclosed |