Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438734 | 0.93 | TSHR (0.45) | TSHRALDH1A1GAANPSR1LMNA | |
| SCHEMBL2608608 | 0.90 | TSHR (0.47) | TSHRALDH1A1GAACYP2C19HPGD | |
| SCHEMBL10015729 | 0.88 | TSHR (0.46) | TSHRALDH1A1GAACYP2C19HPGD | |
| SCHEMBL9338985 | 0.87 | ESR1 (0.47) | TSHRALDH1A1GAALMNAMAPT | |
| SCHEMBL13163893 | 0.86 | POLB (0.44) | TSHRALDH1A1GAANPSR1LMNA | |
| SCHEMBL22828266 | 0.83 | BACE1 (0.51) | TSHRALDH1A1GAANPSR1LMNA | |
| SCHEMBL14570628 | 0.82 | KMT2A (0.49) | TSHRALDH1A1GAANPSR1MAPT | |
| SCHEMBL17753754 | 0.81 | ALDH1A1 (0.44) | TSHRALDH1A1GAACYP2C19HPGD | |
| SCHEMBL14682197 | 0.81 | CFD (0.42) | TSHRALDH1A1MAPTNR3C1TNFSF11 | |
| SCHEMBL5034647 | 0.80 | ESR1 (0.62) | ALDH1A1CYP2C19HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8396399-B2 | Toner bearing member, developing device, image forming apparatus, and image forming method | RICOH COMPANY, LTD. (JP) | 2013-03-12 | — | — | US | disclosed |
| US-8369755-B2 | Developing device and image forming apparatus using the developing device | RICOH COMPANY, LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20110176835-A1 | TONER BEARING MEMBER, DEVELOPMENT DEVICE, AND IMAGE FORMING APPARATUS | RICOH COMPANY, LTD (JP) | 2011-07-21 | — | — | US | disclosed |
| US-20100329748-A1 | DEVELOPING DEVICE AND IMAGE FORMING APPARATUS USING THE DEVELOPING DEVICE | RICOH COMPANY, LTD. (JP) | 2010-12-30 | — | — | US | disclosed |
| US-20100303509-A1 | Toner Bearing Member, Developing Device, Image Forming Apparatus, And Image Forming Method | RICOH COMPANY, LTD. (JP) | 2010-12-02 | — | — | US | disclosed |