Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | GNPAT | O15228 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 2/20 | 0.42 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bisorcic SCHEMBL2109666 | 0.88 | FOLH1 (0.64) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| Bisorcic SCHEMBL16238411 | 0.88 | FOLH1 (0.64) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| Bisorcic SCHEMBL2109664 | 0.88 | FOLH1 (0.64) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL16393150 | 0.86 | FOLH1 (0.71) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL1200060 | 0.86 | FOLH1 (0.71) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL2735591 | 0.86 | FOLH1 (0.71) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL9800454 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL9800461 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL648868 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EMAPTTHRBALOX15 | |
| SCHEMBL648867 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178292-A1 | SYNTHESIS OF CYCLIC AMIDINES | BITOP AG (DE) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178292-A1 | SYNTHESIS OF CYCLIC AMIDINES | ODC1, PAM, COASY | SMN1; SMN2 4414/4885KDM4E 3917/4885MAPT 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.