Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.53 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | SELP | P16109 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1453516 | 0.95 | HPGD (0.66) | HPGDFFAR4FFAR1FFAR2PPARA | |
| SCHEMBL2776108 | 0.89 | FFAR4 (0.67) | HPGDFFAR4FFAR1FFAR2 | |
| SCHEMBL7095615 | 0.88 | PPARA (0.59) | PPARASELPALOX5PPARG | |
| SCHEMBL7415347 | 0.86 | PPARA (0.58) | PPARASELPALOX5PPARGMAPT | |
| SCHEMBL7410835 | 0.85 | GAA (0.65) | SELPALOX5GAALMNA | |
| SCHEMBL6172599 | 0.83 | SELP (0.54) | HPGDFFAR4FFAR1PPARASELP | |
| SCHEMBL503571 | 0.83 | PLAAT3 (0.61) | PPARASELPPPARG | |
| SCHEMBL27575315 | 0.82 | FFAR4 (0.59) | HPGDFFAR4FFAR1MAPT | |
| SCHEMBL7824983 | 0.82 | ALOX5 (0.71) | ALOX5GAALMNA | |
| SCHEMBL24238653 | 0.81 | HPGD (0.44) | HPGDPPARAALOX5PPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096377-A1 | PYRROLE COMPOUND | 第一三共株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |