Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.42 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10148307 | 0.86 | SMN1; SMN2 (0.49) | EPHX2ACACBPARP10FAAH | |
| SCHEMBL10148308 | 0.86 | EPHX2 (0.53) | EPHX2ALDH1A1PARP10FAAH | |
| SCHEMBL14235504 | 0.84 | CYP19A1 (0.46) | EPHX2 | |
| SCHEMBL14127724 | 0.84 | CYP19A1 (0.46) | EPHX2 | |
| SCHEMBL10197496 | 0.79 | DGAT1 (0.47) | ALDH1A1FAAH | |
| SCHEMBL16839074 | 0.79 | P2RX3 (0.44) | EPHX2P2RX3MMP13KMT2ACHRNA7 | |
| SCHEMBL13117542 | 0.79 | LMNA (0.51) | EPHX2ALDH1A1KMT2A | |
| SCHEMBL10186118 | 0.79 | LMNA (0.48) | EPHX2KMT2AFAAH | |
| SCHEMBL25273164 | 0.78 | CYP2D6 (0.52) | ALDH1A1KMT2A | |
| SCHEMBL17784008 | 0.78 | CYP2D6 (0.52) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096377-A1 | PYRROLE COMPOUND | 第一三共株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |