Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16200214 | 0.74 | ADORA2A (0.40) | MEN1KMT2A | |
| SCHEMBL24757738 | 0.70 | MEN1 (0.41) | MEN1MAPTRAB9AKMT2ANPSR1 | |
| SCHEMBL18482876 | 0.69 | MEN1 (0.49) | MEN1MAPTRAB9AKMT2ANPSR1 | |
| SCHEMBL13493803 | 0.69 | GAA (0.52) | MEN1MAPTRAB9AKMT2ANPSR1 | |
| SCHEMBL18162861 | 0.68 | CRHR1 (0.37) | MEN1MAPTRAB9AKMT2ANPSR1 | |
| SCHEMBL16833300 | 0.67 | MEN1 (0.54) | MEN1MAPTRAB9AKMT2ANPSR1 | |
| SCHEMBL13693058 | 0.64 | ADORA2A (0.39) | MEN1MAPTKMT2ANR3C1 | |
| SCHEMBL25745868 | 0.64 | HTR2C (0.39) | MEN1MAPTRAB9AKMT2ANPSR1 | |
| SCHEMBL19592061 | 0.64 | MDM2 (0.34) | MEN1MAPTRAB9AKMT2ANPSR1 | |
| SCHEMBL31327140 | 0.64 | KMT2A (0.38) | MEN1MAPTRAB9AKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095450-A1 | CYCLOHEXYL AMIDE DERIVATIVES AS CRF RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2011-08-11 | — | — | WO | disclosed |