Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15679720 | 0.78 | — | — | |
| SCHEMBL1128735 | 0.77 | MAPT (0.37) | MAPTALDH1A1ALOX15KDM4EPOLB | |
| SCHEMBL10792327 | 0.76 | MAPT (0.39) | MAPTALDH1A1ALOX15KDM4EPOLB | |
| SCHEMBL4868570 | 0.74 | ALDH1A1 (0.42) | MAPTALDH1A1ALOX15KDM4EPOLB | |
| SCHEMBL7872308 | 0.74 | — | — | |
| SCHEMBL24862 | 0.74 | ALDH1A1 (0.42) | MAPTALDH1A1ALOX15KDM4EPOLB | |
| SCHEMBL27781831 | 0.74 | ALDH1A1 (0.42) | MAPTALDH1A1ALOX15KDM4EPOLB | |
| Water SCHEMBL27960090 | 0.73 | ALDH1A1 (0.41) | MAPTALDH1A1ALOX15KDM4EPOLB | |
| Ethylene SCHEMBL28206554 | 0.71 | ALDH1A1 (0.41) | MAPTALDH1A1ALOX15KDM4E | |
| SCHEMBL11834828 | 0.71 | MAPT (0.35) | MAPTALDH1A1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12281126-B2 | Inhibitors of cyclin-dependent kinase 7 and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| US-20220089611-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-03-24 | — | — | US | disclosed |
| CN-112020358-A | Small molecules inducing selective degradation of proteins and uses thereof | 达纳-法伯癌症研究所有限公司 | 2020-12-01 | — | — | CN | disclosed |
| EP-3355922-A2 | COMBINATION THERAPY OF BROMODOMAIN INHIBITORS AND CHECKPOINT BLOCKADE | Dana Farber Cancer Institute, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| CN-104114605-B | Method for polymer synthesis | 沙特阿美技术公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-103842082-B | The Catalyst And Method of Macroscopic single crystal | 诺沃梅尔公司 | 2017-07-18 | — | — | CN | disclosed |
| CN-102781909-B | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING INC | 2015-06-17 | — | — | CN | disclosed |
| CN-104114605-A | Method for polymer synthesis | NOVOMER INC | 2014-10-22 | — | — | CN | disclosed |
| CN-103842082-A | Catalysts and methods for polymer synthesis | NOVOMER INC | 2014-06-04 | — | — | CN | disclosed |
| CN-102781909-A | N-alkoxyamide conjugates as imaging agents | LANTHEUS MEDICAL IMAGING INC | 2012-11-14 | — | — | CN | disclosed |
| WO-2011094953-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFLUENZA | F. HOFFMANN-LA ROCHE AG (CH) | 2011-08-11 | — | — | WO | disclosed |
| WO-2011095576-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFLUENZA | F. HOFFMANN-LA ROCHE AG (CH) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12281126-B2 | Inhibitors of cyclin-dependent kinase 7 and uses thereof | CDK9, CDK7, CDK1 | MAPT 949/4885ALDH1A1 4202/4885ALOX15 3720/4885 |
| US-20220089611-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 AND USES THEREOF | CDK9, CDK7, CDK1 | MAPT 949/4885ALDH1A1 4202/4885ALOX15 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.