SCHEMBL12440796

SCHEMBL12440796

CBCc1ccc(C(=O)Nc2cccc3c(NC(=O)c4ccc(CC)cc4)cccc23)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAOK1 Q7L7X3 1/20 0.51
HDAC3 O15379 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC2 Q92769 2/20 0.48
NCOR1 O75376 1/20 0.48
PLK1 P53350 1/20 0.46
SLC16A3 O15427 1/20 0.46
PPARA Q07869 1/20 0.46
NR1H4 Q96RI1 1/20 0.46
NPC1 O15118 5/20 0.46
RAB9A P51151 5/20 0.46
MAPT P10636 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TRPV1 Q8NER1 4/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
HDAC4 P56524 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12440778 0.82 NPC1 (0.49) HDAC3HDAC1HDAC2NCOR1PLK1
SCHEMBL12440780 0.81 RAB9A (0.54) PLK1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL12440757 0.81 NPC1 (0.59) HDAC3HDAC1HDAC2NCOR1PLK1
SCHEMBL12440754 0.79 PLK1 (0.50) PLK1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL18177286 0.79 TAOK1 (0.47) TAOK1HDAC3HDAC1HDAC2NCOR1
SCHEMBL12440808 0.78 EGFR (0.48) PLK1NR1H4NPC1RAB9AMAPT
SCHEMBL12440794 0.78 PLK1 (0.53) PLK1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL12440789 0.78 NR1H4 (0.52) PLK1NR1H4NPC1RAB9AMAPT
SCHEMBL12440769 0.77 NPC1 (0.56) NR1H4NPC1RAB9AMAPTKMT2A
SCHEMBL12993631 0.76 TAOK1 (0.49) TAOK1HDAC3HDAC1HDAC2NCOR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8519040-B2 Ionic organic compound, production method thereof, hydrogelling agent composed of the ionic organic compound, hydrogel containing same, methanol gelling agent, methanol gel containing same, and carbon nanotube dispersant NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2013-08-27 US disclosed
US-20110178218-A1 IONIC ORGANIC COMPOUND, PRODUCTION METHOD THEREOF, HYDROGELLING AGENT COMPOSED OF THE IONIC ORGANIC COMPOUND, HYDROGEL CONTAINING SAME, METHANOL GELLING AGENT, METHANOL GEL CONTAINING SAME, AND CARBON NANOTUBE DISPERSANT National Institute of Avanced Industrial Science and Technology (JP) 2011-07-21 US disclosed