SCHEMBL12440754

SCHEMBL12440754

CBCc1ccc(C(=O)Nc2c(C)c(C)c(NC(=O)c3ccc(CC)cc3)c(C)c2C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 1/20 0.50
NPC1 O15118 6/20 0.46
RAB9A P51151 5/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
PKM P14618 2/20 0.46
DEGS1 O15121 1/20 0.45
TRPV1 Q8NER1 1/20 0.45
ALDH1A1 P00352 4/20 0.44
TDP1 Q9NUW8 1/20 0.44
TAS1R3 Q7RTX0 1/20 0.43
TAS1R1 Q7RTX1 1/20 0.43
MAPT P10636 3/20 0.42
KLF5 Q13887 1/20 0.41
ADCY8 P40145 1/20 0.41
ADCY1 Q08828 1/20 0.41
LMNA P02545 2/20 0.40
GAA P10253 2/20 0.40
HPGD P15428 1/20 0.40
POLB P06746 1/20 0.40
AGTR1 P30556 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12440811 0.86 PLK1 (0.45) PLK1NPC1RAB9ASMN1; SMN2PKM
SCHEMBL12440780 0.85 RAB9A (0.54) PLK1NPC1RAB9ASMN1; SMN2TRPV1
SCHEMBL12440778 0.83 NPC1 (0.49) PLK1NPC1RAB9ASMN1; SMN2PKM
SCHEMBL12440794 0.81 PLK1 (0.53) PLK1NPC1RAB9ASMN1; SMN2TRPV1
SCHEMBL12440789 0.81 NR1H4 (0.52) PLK1NPC1RAB9ASMN1; SMN2PKM
SCHEMBL12440757 0.79 NPC1 (0.59) PLK1NPC1RAB9ASMN1; SMN2PKM
SCHEMBL12440796 0.79 TAOK1 (0.51) PLK1NPC1RAB9ASMN1; SMN2PKM
SCHEMBL12440808 0.79 EGFR (0.48) PLK1NPC1RAB9ASMN1; SMN2PKM
SCHEMBL12440772 0.78 PGR (0.51) NPC1RAB9ASMN1; SMN2TRPV1ALDH1A1
SCHEMBL12440801 0.78 F2 (0.47) PLK1NPC1RAB9ASMN1; SMN2TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8519040-B2 Ionic organic compound, production method thereof, hydrogelling agent composed of the ionic organic compound, hydrogel containing same, methanol gelling agent, methanol gel containing same, and carbon nanotube dispersant NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2013-08-27 US disclosed
US-20110178218-A1 IONIC ORGANIC COMPOUND, PRODUCTION METHOD THEREOF, HYDROGELLING AGENT COMPOSED OF THE IONIC ORGANIC COMPOUND, HYDROGEL CONTAINING SAME, METHANOL GELLING AGENT, METHANOL GEL CONTAINING SAME, AND CARBON NANOTUBE DISPERSANT National Institute of Avanced Industrial Science and Technology (JP) 2011-07-21 US disclosed