SCHEMBL12440907

SCHEMBL12440907

Cc1ccc2c(c1)C(c1ccc(O)c(COC=O)c1)(c1ccc(O)c(COC=O)c1)c1cc(Br)ccc1-2

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.38
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
BIRC5 O15392 2/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
THRB P10828 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
PKM P14618 1/20 0.31
CNR1 P21554 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31
ERN1 O75460 1/20 0.31
PTK2 Q05397 1/20 0.31
HTT P42858 2/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
PIK3CG P48736 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12440922 0.86 FFAR4 (0.36) SRCTHRBHTTALDH1A1
SCHEMBL15430910 0.84 ERN1 (0.32) ESR1ESR2ERN1
SCHEMBL12440912 0.78 SRC (0.30) SRC
SCHEMBL900305 0.77 ESR1 (0.45) ESR1ESR2CSNK2A1PKMCNR1
SCHEMBL13429588 0.74 CA12 (0.43) ESR1ESR2CSNK2A1MAOAMAOB
SCHEMBL15430916 0.73 PDK2 (0.33) SRC
SCHEMBL13828488 0.73 SRC (0.38) SRCHTTALDH1A1HPGD
SCHEMBL12440923 0.72 MAPT (0.36) ERN1ALDH1A1HPGD
SCHEMBL5147567 0.72 ESR1 (0.40) ESR1ESR2BIRC5CSNK2A2CSNK2B
SCHEMBL4072602 0.71 ESR1 (0.64) ESR1ESR2PKMERN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318706-B2 Laminated structure, method for producing same, and electronic element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 SRC 752/4885ESR1 67/4885ESR2 212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.