SCHEMBL12440923

SCHEMBL12440923

COc1ccc(C2(c3ccc(OC)c(OC=O)c3)c3cc(C)ccc3-c3ccc(Br)cc32)cc1OC=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ACHE P22303 1/20 0.36
STAT3 P40763 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP2C19 P33261 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP2C9 P11712 1/20 0.34
AMY1A P0DUB6 1/20 0.33
APP P05067 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ERN1 O75460 1/20 0.32
NPC1 O15118 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CDK4 P11802 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12440922 0.82 FFAR4 (0.36) MAPTLMNAMEN1KMT2ASTAT3
SCHEMBL12440908 0.82
SCHEMBL12374347 0.81 ACHE (0.55) MAPTLMNAMEN1KMT2AACHE
SCHEMBL4760269 0.77 NQO2 (0.41) MAPTLMNAMEN1KMT2ACYP1A2
SCHEMBL14725300 0.75 TSHR (0.46) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL12374328 0.74 ACHE (0.44) MAPTLMNAMEN1KMT2AACHE
SCHEMBL13494976 0.74 ALDH1A1 (0.41) MAPTMEN1KMT2AACHEALDH1A1
SCHEMBL12440907 0.72 SRC (0.38) ALDH1A1ERN1HPGD
SCHEMBL13567251 0.72 ALDH1A1 (0.44) MAPTLMNAMEN1KMT2ACYP1A2
SCHEMBL16656146 0.72 ALDH1A1 (0.42) MAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318706-B2 Laminated structure, method for producing same, and electronic element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 MAPT 456/4885LMNA 331/4885MEN1 1758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.