Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | PKM | P14618 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.58 |
| ▸ | METAP1 | P53582 | 2/20 | 0.55 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 9/20 | 0.46 |
| ▸ | SNCA | P37840 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124459 | 0.79 | ITGA4 (0.58) | MAPTMEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL13184661 | 0.74 | MAPT (0.79) | MAPTMEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL29350119 | 0.73 | MAPT (1.00) | MAPTMEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL13184630 | 0.73 | MAPT (1.00) | MAPTMEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL13184632 | 0.73 | MAPT (0.81) | MAPTMEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL8026269 | 0.72 | METAP1 (1.00) | MAPTMEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL13184656 | 0.72 | MAPT (0.79) | MAPTMEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL13184631 | 0.71 | MAPT (0.78) | MAPTMEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL14713028 | 0.70 | MAPT (0.67) | MAPTMEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL12218472 | 0.70 | MAPT (0.61) | MAPTMEN1PKMKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2008-01-03 | — | — | US | disclosed |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | OPTIMER PHOTONICS, INC. (US) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059163-A1 | Non-linear opticaly active molecules, their synthesis, and use | INCENP, CYBA, ADCY5 | MAPT 2242/4885MEN1 4480/4885PKM 447/4885 |
| US-20080004415-A1 | Non-linear optically active molecules, their synthesis, and use | INCENP, CYBA, PAICS | MAPT 2173/4885MEN1 4473/4885PKM 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.