Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18002172 | 0.91 | HDAC8 (0.54) | ALDH1A1DRD2DRD4DRD3ATM | |
| SCHEMBL28469757 | 0.87 | ALDH1A1 (0.54) | ALDH1A1DRD2DRD4DRD3LMNA | |
| SCHEMBL9400665 | 0.87 | VEGFA (0.56) | ALDH1A1DRD2DRD4DRD3KDM4E | |
| SCHEMBL18001993 | 0.86 | MAPK14 (0.52) | ALDH1A1HDAC6KDM4ELMNANPSR1 | |
| SCHEMBL28469317 | 0.85 | MAPT (0.55) | ALDH1A1ATMHDAC8HDAC6KDM4E | |
| SCHEMBL28477450 | 0.85 | ALDH1A1 (0.49) | ALDH1A1DRD2DRD4DRD3ATM | |
| SCHEMBL25753482 | 0.84 | ALDH1A1 (0.48) | ALDH1A1DRD2DRD4DRD3ATM | |
| SCHEMBL17894526 | 0.83 | KDM4E (0.58) | ALDH1A1KDM4ELMNASMN1; SMN2HTT | |
| SCHEMBL1609235 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HDAC8HDAC6KDM4ELMNA | |
| SCHEMBL17894535 | 0.81 | ALDH1A1 (0.55) | ALDH1A1ATMKDM4ESMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047226-B | Matrine pyrrole and indole derivatives, and preparation method and application thereof | 广西大学 | 2020-11-03 | — | — | CN | claimed |
| CN-108358923-B | Sophoridine pyrrole and indole derivatives, and preparation method and application thereof | 广西大学 | 2020-11-03 | — | — | CN | claimed |
| CN-107033058-A | The synthesis technique of azacyclo- high selectivity aldehyde | 江苏斯威森生物医药工程研究中心有限公司 | 2017-08-11 | — | — | CN | claimed |
| CN-112239468-B | Metal-free solvent-free synthesis of fused pyridine heterocycles and biomedical applications thereof | 印多尔印度理工学院 | 2025-05-27 | — | — | CN | disclosed |
| CN-117486785-A | Synthesis method of chiral piperidinol derivative | 长兴宜生药物科技有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-11427596-B2 | Metal-free solvent-free synthesis of fused-pyrido heterocycles and biomedical applications | Indian Institute of Technology Indore (IN) | 2022-08-30 | — | — | US | disclosed |
| CN-113480471-A | Multi-chiral nitrogen-substituted piperidinol derivative and preparation method thereof | 长兴宜生药物科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| US-20210070765-A1 | METAL-FREE SOLVENT-FREE SYNTHESIS OF FUSED-PYRIDO HETEROCYCLES AND BIOMEDICAL APPLICATIONS | Indian Institute of Technology Indore (IN) | 2021-03-11 | — | — | US | disclosed |
| WO-2021014463-A1 | METAL-FREE SOLVENT-FREE SYNTHESIS OF FUSED-PYRIDO HETEROCYCLES AND BIOMEDICAL APPLICATIONS | CHELVAM VENKATESH (IN) | 2021-01-28 | — | — | WO | disclosed |
| CN-112239468-A | Metal-free and solvent-free synthesis of fused pyridine heterocycles and biomedical applications thereof | 文卡特什·切尔姆 | 2021-01-19 | — | — | CN | disclosed |
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | THE UNIVERSITY OF BATH (GB) | 2017-11-30 | — | — | US | disclosed |
| EP-1142872-A1 | AROMATIC HETEROCYCLE COMPOUNDS HAVING HIV INTEGRASE INHIBITING ACTIVITIES | SHIONOGI & CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001016104-A1 | CYCLOPROPYLINDOLE DERIVATIVES | SPIROGEN LIMITED (GB) | 2001-03-08 | — | — | WO | disclosed |
| US-6063789-A | Aminoisoquinolines and aminotheinopyridine derivatives and their use as anti-inflammatory agents | ASTRA PHARMACEUTICALS, LTD. (GB) | 2000-05-16 | — | — | US | disclosed |
| WO-1997049708-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1997-12-31 | — | — | WO | disclosed |
| EP-0592366-A1 | Photochromic compounds, their preparation and their use | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| EP-0077024-B1 | IMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-08-12 | — | — | EP | disclosed |
| US-4585771-A | Antiinflammatory imidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| US-4466976-A | Antiinflammatory and antiallergic imidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-08-21 | — | — | US | disclosed |
| EP-0077024-A2 | Imidazole derivatives, process for their preparation and pharmaceutical products containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | ZYX, MPO, CFB | ALDH1A1 1734/4885DRD2 2272/4885DRD4 1099/4885 |
| US-11427596-B2 | Metal-free solvent-free synthesis of fused-pyrido heterocycles and biomedical applications | SLC11A2, WEE1, BRCA1 | ALDH1A1 2132/4885DRD2 2240/4885DRD4 3649/4885 |
| US-20210070765-A1 | METAL-FREE SOLVENT-FREE SYNTHESIS OF FUSED-PYRIDO HETEROCYCLES AND BIOMEDICAL APPLICATIONS | SLC11A2, WEE1, BRCA1 | ALDH1A1 2132/4885DRD2 2240/4885DRD4 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.