SCHEMBL1244286

SCHEMBL1244286

NCCc1c[c]ccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27868131 0.98 TAAR1 (0.50)
SCHEMBL8099957 0.87 MAOA (0.48)
SCHEMBL27501547 0.85 MAOA (0.57)
SCHEMBL3169832 0.82
SCHEMBL232726 0.81
SCHEMBL27636904 0.81 LOXL2 (0.44)
SCHEMBL27617806 0.81 MAOB (0.59)
SCHEMBL28791637 0.79
SCHEMBL159206 0.79 MAOA (0.44)
SCHEMBL27649927 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109661399-A Cross-coupling methods 芝诺罗耶尔蒂里程碑有限责任公司 2019-04-19 CN claimed
CN-109503591-A Pharmaceutical composition, its solid form and their purposes of dihydro pyrazine and pyrazine compound 西格诺药品有限公司 2019-03-22 CN claimed
CN-107531672-A CHEMICAL PROCESS FOR PREPARING PYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF 诺华股份有限公司 2018-01-02 CN claimed
CN-107474051-A Pharmaceutical composition, its solid form and their purposes of dihydro pyrazine and pyrazine compound 西格诺药品有限公司 2017-12-15 CN claimed
WO-2011151669-A1 PROCESS FOR PRODUCING ENANTIOMERICALLY ENRICHED ISOMER OF 3-(1-AMINOETHYL) PHENYL DERIVATIVE AND EMPLOYING THE SAME TO PRODUCE RIVASTIGMINE OR ITS PHARMACEUTICALLY ACCEPTABLE SALT JUBILANT LIFE SCIENCES LIMITED (IN) 2011-12-08 WO claimed
JP-2011524881-A 2011-09-08 JP claimed
CN-102123991-A 2-arylaminoquinazolines for the treatment of proliferative diseases NOVARTIS AG 2011-07-13 CN claimed
EP-2307385-A1 2 -ARYLAMINOQUINAZOLINES FOR TREATING PROLIFERATIVE DISEASES Novartis AG (CH) 2011-04-13 EP claimed
US-20100121052-A1 Novel compounds for treating proliferative diseases JAIN RAMA 2010-05-13 US claimed
WO-2009153313-A1 2 -ARYLAMINOQUINAZOLINES FOR TREATING PROLIFERATIVE DISEASES NOVARTIS AG (CH) 2009-12-23 WO claimed
CN-101048371-A Process for alkylaryl sulfide derivatives and novel sulfides KANG HEONJOONG (KR) 2007-10-03 CN claimed
US-6916957-B2 Serine protease inhibitors TULARIK LIMITED (GB) 2005-07-12 US claimed
EP-0706536-B1 THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE, COMPOSITIONS CONTAINING THE SAME PROCTER & GAMBLE (US) 2000-05-17 EP claimed
CN-114573566-B Selective ROCK2 kinase inhibitors 杭州邦顺制药有限公司 2023-05-30 CN disclosed
CN-114787143-A ZESTE enhancer homolog 2 inhibitors and uses thereof 四川海思科制药有限公司 2022-07-22 CN disclosed
CN-114573566-A Selective ROCK2 kinase inhibitors 杭州邦顺制药有限公司 2022-06-03 CN disclosed
EP-0715638-A1 SILICONE GRAFTED THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1996-06-12 EP disclosed
EP-0706536-A1 THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE, COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1996-04-17 EP disclosed
WO-1995006078-A1 SILICONE GRAFTED THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1995-03-02 WO disclosed
WO-1995001383-A1 THERMOPLASTIC ELASTOMERIC COPOLYMERS AND HAIR AND SKIN CARE, COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 1995-01-12 WO disclosed