Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099957 | 0.94 | MAOA (0.48) | MAOAHRH1HTR2ACYP2A6SIGMAR1 | |
| SCHEMBL1244286 | 0.85 | — | — | |
| SCHEMBL8790864 | 0.84 | MAOA (0.38) | MAOAHRH1HTR2ASIGMAR1MAOB | |
| SCHEMBL27868131 | 0.83 | TAAR1 (0.50) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL920960 | 0.83 | MAOA (0.50) | MAOAHTR2ASIGMAR1MAOB | |
| SCHEMBL922424 | 0.82 | SIGMAR1 (0.50) | MAOASIGMAR1MAOB | |
| SCHEMBL3608427 | 0.82 | MAOA (0.34) | MAOAHTR2ASIGMAR1 | |
| SCHEMBL7367065 | 0.80 | MAOA (0.33) | MAOASIGMAR1MAOB | |
| SCHEMBL278144 | 0.80 | TDP1 (0.47) | HTR2A | |
| SCHEMBL4849823 | 0.80 | CA2 (0.42) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1144802-A | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1997-03-12 | — | — | CN | disclosed |