SCHEMBL1244366

SCHEMBL1244366

OOc1cccc(O)c1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.61
ALDH1A1 P00352 4/20 0.61
HPGD P15428 3/20 0.61
ALOX15 P16050 3/20 0.61
HSD17B10 Q99714 3/20 0.61
MAPT P10636 3/20 0.61
TP53 P04637 2/20 0.61
KDM4E B2RXH2 2/20 0.61
CYP3A4 P08684 2/20 0.61
ALOX12 P18054 1/20 0.61
MAPK1 P28482 1/20 0.61
CA2 P00918 4/20 0.58
CA1 P00915 3/20 0.58
EGFR P00533 2/20 0.58
FYN P06241 2/20 0.58
MMP9 P14780 2/20 0.58
RECQL P46063 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
CDK2 P24941 2/20 0.58
ADAMTS4 O75173 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8429914 0.80
SCHEMBL88340 0.80 LMNA (0.64) LMNAALDH1A1HPGDALOX15HSD17B10
3-Methoxycatechol SCHEMBL67332 0.76 TP53 (1.00) LMNAALDH1A1HPGDALOX15HSD17B10
SCHEMBL5595646 0.76 ALDH1A1 (0.58) LMNAALDH1A1HPGDALOX15HSD17B10
3-Methoxycatechol SCHEMBL29477155 0.76 TP53 (1.00) LMNAALDH1A1HPGDALOX15HSD17B10
SCHEMBL1788357 0.76 LMNA (0.58) LMNAALDH1A1HPGDALOX15HSD17B10
SCHEMBL37622 0.76 ALOX15 (0.58) LMNAALDH1A1HPGDALOX15HSD17B10
SCHEMBL10611186 0.76 ALDH1A1 (0.58) LMNAALDH1A1HPGDALOX15HSD17B10
SCHEMBL7477685 0.76 LMNA (0.58) LMNAALDH1A1HPGDALOX15HSD17B10
SCHEMBL28467007 0.76 LMNA (0.58) LMNAALDH1A1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0652043-B1 Aromatic polyetherketone gas separation membranes AIR LIQUIDE (FR) 2002-06-12 EP claimed
EP-3224318-B1 WEATHERABLE THERMOPLASTIC COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREFROM SHPP GLOBAL TECH BV (NL) 2023-09-13 EP disclosed
US-10144827-B2 Weatherable thermoplastic compositions, method of manufacture, and articles therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-12-04 US disclosed
EP-3004236-B1 COLOR-STABLE THERMOPLASTIC COMPOSITION SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-07-18 EP disclosed
CN-105246961-B Color stable thermoplastic composition 沙特基础全球技术有限公司 2018-05-15 CN disclosed
US-20170306147-A1 WEATHERABLE THERMOPLASTIC COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-10-26 US disclosed
EP-3224318-A1 WEATHERABLE THERMOPLASTIC COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREFROM SABIC Global Technologies B.V. (NL) 2017-10-04 EP disclosed
US-9708465-B2 Color-stable thermoplastic composition SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-07-18 US disclosed
WO-2016085790-A1 WEATHERABLE THERMOPLASTIC COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-02 WO disclosed
EP-3004236-A1 COLOR-STABLE THERMOPLASTIC COMPOSITION SABIC Global Technologies B.V. (NL) 2016-04-13 EP disclosed
US-5891626-A ENZYME-LINKED ANALYSIS; USING SURFACTANT TROPIX, INC. (US) 1999-04-06 US disclosed
EP-0352713-B2 Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes TROPIX INC (US) 1998-07-08 EP disclosed
CN-1088956-A Contain stable state 1, the composition and the application thereof of 2-dioxane and the fluorescent chemicals that interrelates with narrow spacing with it UNIV WAYNE STATE (US) 1994-07-06 CN disclosed
EP-0518387-A2 Method and composition providing enhanced chemiluminescence from 1,2-dioxetanes TROPIX, INC. (US) 1992-12-16 EP disclosed
EP-0510721-A2 Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes TROPIX, INC. (US) 1992-10-28 EP disclosed
US-5004565-A Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes THE BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) 1991-04-02 US disclosed
US-4959182-A Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) 1990-09-25 US disclosed
CN-1040980-A Compositions for enhancing chemiluminescence of 1, 2-dioxetanes UNIV WAYNE STATE (US) 1990-04-04 CN disclosed
EP-0352713-A1 Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes TROPIX, INC. (US) 1990-01-31 EP disclosed
US-4749643-A 1-ALKYLAMINO-3-CYANOMETHYLENE-1-CYCLOHEXENE COMPOUND AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1988-06-07 US disclosed