Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | PLK1 | P53350 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12445325 | 0.90 | SMN1; SMN2 (0.40) | KMT2ALMNAEPHX2NR1H4TSHR | |
| SCHEMBL12445333 | 0.88 | HPGD (0.50) | LMNATSHRSMN1; SMN2MMP13ALDH1A1 | |
| SCHEMBL12630364 | 0.75 | GAA (0.55) | KMT2ALMNAEPHX2HDAC1HDAC6 | |
| SCHEMBL6859304 | 0.72 | KMT2A (1.00) | KMT2ALMNAEPHX2NR1H4TSHR | |
| SCHEMBL13035939 | 0.70 | KMT2A (0.54) | KMT2ALMNAEPHX2NR1H4HDAC1 | |
| SCHEMBL12893241 | 0.70 | GAA (0.61) | KMT2ALMNAEPHX2NR1H4HDAC1 | |
| SCHEMBL13878429 | 0.69 | MMP13 (0.47) | KMT2ATSHRSMN1; SMN2MMP13ALDH1A1 | |
| SCHEMBL12856272 | 0.68 | KMT2A (0.73) | KMT2ALMNATSHRMEN1HSD17B10 | |
| SCHEMBL14498108 | 0.67 | EPHX2 (0.46) | KMT2ALMNAEPHX2NR1H4TSHR | |
| SCHEMBL12445332 | 0.66 | MGAM (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865380-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2014-10-21 | — | — | US | disclosed |
| US-20110177438-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2011-07-21 | — | — | US | disclosed |