Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 7/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12445325 | 0.89 | SMN1; SMN2 (0.40) | MAPTRAB9AHTTSMN1; SMN2TSHR | |
| SCHEMBL12445336 | 0.88 | KMT2A (0.51) | SMN1; SMN2TSHRMMP13LMNAALDH1A1 | |
| SCHEMBL13878429 | 0.81 | MMP13 (0.47) | HPGDMAPTRAB9AHTTSMN1; SMN2 | |
| SCHEMBL12630364 | 0.74 | GAA (0.55) | HPGDRAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3301210 | 0.71 | HPGD (1.00) | HPGDMAPTRAB9AHTTSMN1; SMN2 | |
| SCHEMBL203697 | 0.71 | HPGD (1.00) | HPGDMAPTRAB9AHTTSMN1; SMN2 | |
| SCHEMBL13035939 | 0.69 | KMT2A (0.54) | HPGDMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL258765 | 0.69 | RAB9A (0.55) | HPGDMAPTRAB9AHTTSMN1; SMN2 | |
| SCHEMBL12893241 | 0.69 | GAA (0.61) | HPGDMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL14498108 | 0.66 | EPHX2 (0.46) | HPGDMAPTRAB9AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865380-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2014-10-21 | — | — | US | disclosed |
| US-20110177438-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2011-07-21 | — | — | US | disclosed |