Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2326810 | 0.76 | KMT2A (0.60) | L3MBTL1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2325585 | 0.76 | CYP1A2 (0.60) | L3MBTL1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL3471739 | 0.74 | L3MBTL1 (0.56) | L3MBTL1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2332209 | 0.74 | L3MBTL1 (0.56) | L3MBTL1MAPTALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2333412 | 0.73 | L3MBTL1 (0.57) | L3MBTL1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL13310979 | 0.69 | KMT2A (0.63) | L3MBTL1MAPTALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2333286 | 0.69 | SMN1; SMN2 (0.52) | L3MBTL1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2333441 | 0.68 | S1PR2 (0.61) | L3MBTL1MAPTALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2333538 | 0.68 | KMT2A (0.65) | L3MBTL1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2335805 | 0.68 | ALDH1A1 (1.00) | L3MBTL1MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097600-A1 | SCREENING METHOD AND COMPOUNDS FOR MODULATING TELOMERASE ACTIVITY | THE WISTAR INSTITUTE (US) | 2011-08-11 | — | — | WO | disclosed |