Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11980220 | 0.68 | PTGS1 (0.39) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL15979463 | 0.63 | PTGS1 (0.40) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL16546105 | 0.59 | BCL2 (0.42) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL12288020 | 0.59 | PTGS1 (0.33) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL14645953 | 0.57 | PTGS1 (0.32) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL18045592 | 0.56 | PTPRC (0.47) | KDM4EHPGD | |
| SCHEMBL17865606 | 0.54 | PBRM1 (0.31) | HSD17B10 | |
| SCHEMBL22807709 | 0.54 | PTGS1 (0.32) | PTGS1PTGS2KDM4EMT-CO1MT-CO2 | |
| SCHEMBL15763745 | 0.53 | PNMT (0.35) | — | |
| SCHEMBL8254678 | 0.53 | PKM (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011098495-A1 | METHOD OF MAKING COUPLED HETEROARYL COMPOUNDS VIA REARRANGEMENT OF HALOGENATED HETEROAROMATICS FOLLOWED BY OXIDATIVE COUPLING | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-08-18 | — | — | WO | disclosed |