Acridine

Acridine

SCHEMBL1244874

N=S(=O)=O.c1ccc2nc3ccccc3cc2c1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.71
HPGD P15428 3/20 0.71
MAPT P10636 3/20 0.71
GLA P06280 2/20 0.71
ACHE P22303 1/20 0.71
HTR3A P46098 1/20 0.52
NQO2 P16083 2/20 0.48
KMT2A Q03164 4/20 0.45
RAB9A P51151 3/20 0.45
NPC1 O15118 3/20 0.45
KDM4E B2RXH2 2/20 0.45
GAA P10253 2/20 0.45
POLB P06746 2/20 0.45
LMNA P02545 1/20 0.45
PTBP1 P26599 1/20 0.45
RCE1 Q9Y256 1/20 0.45
TDP1 Q9NUW8 1/20 0.42
STAT3 P40763 1/20 0.42
IKBKB O14920 1/20 0.41
PDE2A O00408 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acridine SCHEMBL4972293 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL8339 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL1772714 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL3045498 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL29352289 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL28830169 0.82 MAPT (0.83) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL618814 0.82 ALDH1A1 (0.94) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL10801271 0.82 ALDH1A1 (0.94) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL5182487 0.82 ALDH1A1 (0.94) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL641951 0.82 ALDH1A1 (0.94) ALDH1A1HPGDMAPTGLAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110487777-A The method that acridinium ester chemiluminescent detects HLA-G prediction pre-eclampsia SHAOXING KANGYUE BIOLOGICAL TECH CO LTD 2019-11-22 CN claimed
CN-110058028-A A kind of bis- hydroxy-vitamine D immunity detection reagents of 24,25- and its application 苏州长光华医生物医学工程有限公司 2019-07-26 CN claimed
CN-109283171-A A kind of screening technique of chemical illuminating reagent stabilizer 苏州长光华医生物医学工程有限公司 2019-01-29 CN claimed
CN-108344869-A A kind of hepatitis B surface antigen chemiluminescence immune detection reagent kit and its application 苏州长光华医生物医学工程有限公司 2018-07-31 CN claimed
CN-105264377-B Degradable cationic surface active agent and its purposes in enhanced chemiluminescence 西门子医疗保健诊断公司 2017-09-08 CN claimed
EP-1358344-B1 Dendritic chemiluminescent substrates APPLERA CORP (US) 2007-08-29 EP claimed
US-20070184491-A1 Dendritic chemiluminescent substrates APPLIED BIOSYSTEMS, INC. 2007-08-09 US claimed
EP-1049933-B1 MEASUREMENT OF HYDRIDE USING CHEMILUMINESCENT ACRIDINIUM COMPOUNDS BAYER AG (US) 2005-09-14 EP claimed
EP-1358344-A4 DENDRITIC CHEMILUMINESCENT SUBSTRATES APPLERA CORP (US) 2004-11-03 EP claimed
US-6673560-B1 USE IN DETECTION OF METAL HYDRIDES, ENZYME COFACTORS OR DIAGNOSTIC/MEDICAL DIAGNOSTIC ASSAYS USING DEHYDROGENASES AS REAGENTS, INDICATORS, MARKERS, OR LABELS BAYER CORPORATION 2004-01-06 US claimed
EP-1358344-A2 Dendritic chemiluminescent substrates TROPIX, INC. (US) 2003-11-05 EP claimed
US-20020155523-A1 Chemiluminescent substrate for use as diagnostic tool in analysis of macromolecules APPLIED BIOSYSTEMS, INC. 2002-10-24 US claimed
WO-2002057745-A2 DENDRITIC CHEMILUMINESCENT SUBSTRATES TROPIX, INC. (US) 2002-07-25 WO claimed
EP-1049933-A1 MEASUREMENT OF HYDRIDE USING CHEMILUMINESCENT ACRIDINIUM COMPOUNDS Bayer Corporation (US) 2000-11-08 EP claimed
WO-2000031543-A1 MEASUREMENT OF HYDRIDE USING CHEMILUMINESCENT ACRIDINIUM COMPOUNDS BAYER CORPORATION (US) 2000-06-02 WO claimed
CN-112986221-B Method for detecting object to be detected in sample and kit thereof 利多(香港)有限公司 2024-10-22 CN disclosed
CN-110487777-A The method that acridinium ester chemiluminescent detects HLA-G prediction pre-eclampsia SHAOXING KANGYUE BIOLOGICAL TECH CO LTD 2019-11-22 CN disclosed
EP-0273115-B1 Chemiluminescent acridinium and phenanthridinium salts ABBOTT LAB (US) 1994-09-07 EP disclosed
EP-0273115-A2 Chemiluminescent acridinium and phenanthridinium salts ABBOTT LABORATORIES (US) 1988-07-06 EP disclosed
EP-0273115-A2 Chemiluminescent acridinium and phenanthridinium salts ABBOTT LABORATORIES (US) 1988-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020155523-A1 Chemiluminescent substrate for use as diagnostic tool in analysis of macromolecules LPO, DCLRE1B, LIG3 ALDH1A1 1047/4885HPGD 420/4885MAPT 3490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.