SCHEMBL1244976

SCHEMBL1244976

O=P(c1cccc2ccccc12)(c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
LMNA P02545 2/20 0.53
POLB P06746 1/20 0.53
ALDH1A1 P00352 5/20 0.46
CYP2A6 P11509 3/20 0.46
HSD17B10 Q99714 3/20 0.46
TSHR P16473 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
ACP3 P15309 1/20 0.45
PTK2B Q14289 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A2 P05177 2/20 0.42
HPGD P15428 2/20 0.42
CYP3A4 P08684 1/20 0.42
KEAP1 Q14145 1/20 0.42
MMP3 P08254 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HPRT1 P00492 1/20 0.42
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29380351 1.00 KDM4E (0.53) KDM4ELMNAPOLBALDH1A1CYP2A6
SCHEMBL14339282 0.95 KDM4E (0.50) KDM4ELMNAPOLBALDH1A1CYP2A6
SCHEMBL14339297 0.95 KDM4E (0.50) KDM4ELMNAPOLBALDH1A1CYP2A6
SCHEMBL18372086 0.89 ALDH1A1 (0.46) KDM4ELMNAPOLBALDH1A1CYP2A6
SCHEMBL29613091 0.88 CYP2A6 (0.54) KDM4ELMNAPOLBALDH1A1CYP2A6
SCHEMBL14339289 0.87 KDM4E (0.47) KDM4ELMNAPOLBALDH1A1CYP2A6
SCHEMBL14339269 0.87 KDM4E (0.47) KDM4ELMNAPOLBALDH1A1CYP2A6
SCHEMBL9422307 0.87 POLB (0.47) KDM4ELMNAPOLBALDH1A1CYP2A6
SCHEMBL31212642 0.87 KDM4E (0.47) KDM4ELMNAPOLBALDH1A1CYP2A6
SCHEMBL11451532 0.87 KDM4E (0.47) KDM4ELMNAPOLBALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365726-A1 PROCESS FOR PREPARING HIGH-REACTIVITY ISOBUTENE HOMO- OR COPOLYMERS BASF SE (DE) 2023-11-16 US claimed
EP-4192887-A1 PROCESS FOR PREPARING HIGH-REACTIVITY ISOBUTENE HOMO- OR COPOLYMERS BASF SE (DE) 2023-06-14 EP claimed
CN-116075531-A Process for preparing highly reactive isobutylene homo-or copolymers 巴斯夫欧洲公司 2023-05-05 CN claimed
CN-114573636-A P, N chiral quinoxaline compound and preparation method and application thereof 中国科学院兰州化学物理研究所 2022-06-03 CN claimed
WO-2022028951-A1 PROCESS FOR PREPARING HIGH-REACTIVITY ISOBUTENE HOMO- OR COPOLYMERS BASF SE (DE) 2022-02-10 WO claimed
EP-3950736-A1 PROCESS FOR PREPARING HIGH-REACTIVITY ISOBUTENE HOMO- OR COPOLYMERS BASF SE (DE) 2022-02-09 EP claimed
EP-2481760-B1 INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP claimed
US-7582691-B2 Poly(arylene ether) compositions and articles SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-09-01 US claimed
JP-4311938-B2 2009-08-12 JP claimed
WO-2008089314-A1 FLAME RETARDANT POLY (ARLENE ETHER) COMPOSITIONS AND ARTICLES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-07-24 WO claimed
JP-2004533413-A 2004-11-04 JP claimed
US-20040121990-A1 Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom GREAT LAKES CHEMICAL CORPORATION 2004-06-24 US claimed
US-6733698-B2 Mixture of mono-, bis- and tris-(hydroxyaryl) phosphine oxides useful to make polyglycidyl ethers or in epoxy compositions PABU SERVICES, INC. 2004-05-11 US claimed
EP-1363922-A2 NOVEL HYDROXYARYL PHOSPHINE OXIDES, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM Pabu Services, Inc. (US) 2003-11-26 EP claimed
US-20030148109-A1 Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins CHEMTURA CORPORATION 2003-08-07 US claimed
US-20020168527-A1 Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom GREAT LAKES CHEMICAL CORPORATION 2002-11-14 US claimed
WO-2002066485-A2 NOVEL HYDROXYARYL PHOSPHINE OXIDES, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM PABU SERVICES, INC. (US) 2002-08-29 WO claimed
EP-0274795-B1 PROCESS FOR THE CARBONYLATION OF OLEFINICALLY UNSATURATED COMPOUNDS WITH A PALLADIUM CATALYST SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-08-21 EP claimed
US-4960926-A Process for the carbonylation of olefinically unsaturated compounds with a palladium catalyst SHELL OIL COMPANY (US) 1990-10-02 US claimed
EP-0274795-A2 Process for the carbonylation of olefinically unsaturated compounds with a palladium catalyst SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-07-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040121990-A1 Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom PFAS, PTPMT1, PWWP2B KDM4E 1037/4885LMNA 724/4885POLB 1131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.