Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1625507 | 0.89 | ATM (0.50) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL1226943 | 0.75 | TAAR1 (0.44) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL2682423 | 0.71 | TSHR (0.39) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL11361183 | 0.71 | ATM (0.50) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL8992600 | 0.68 | ATM (0.52) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL2066381 | 0.67 | ATM (0.55) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL6258542 | 0.66 | DRD2 (0.68) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL5050252 | 0.65 | TSHR (0.40) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL5857455 | 0.65 | ATM (0.57) | ATMCYP2D6DRD2DRD4OPRM1 | |
| SCHEMBL28481925 | 0.64 | DRD2 (0.59) | ATMCYP2D6DRD2DRD4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238199-B1 | ADDITIVE MIXTURES FOR STYRENIC POLYMERS | BASF SE (DE) | 2011-08-31 | — | — | EP | disclosed |