Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821376 | 0.83 | GAA (0.60) | GAAPOLBHPGDALDH1A1KDM4E | |
| SCHEMBL9821379 | 0.83 | GAA (0.60) | GAAPOLBHPGDALDH1A1KDM4E | |
| SCHEMBL12275406 | 0.71 | ALDH1A1 (0.64) | GAAPOLBHPGDALDH1A1KDM4E | |
| SCHEMBL12275405 | 0.71 | ALDH1A1 (0.64) | GAAPOLBHPGDALDH1A1KDM4E | |
| SCHEMBL24727855 | 0.69 | SMN1; SMN2 (0.44) | GAAPOLBHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4956254 | 0.67 | POLB (0.57) | GAAPOLBHPGDALDH1A1KDM4E | |
| SCHEMBL28282172 | 0.66 | KMT2A (0.46) | GAAPOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9821551 | 0.65 | POLB (0.48) | GAAPOLBHPGDALDH1A1KDM4E | |
| SCHEMBL2608307 | 0.63 | NPC1 (1.00) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL11743247 | 0.63 | NPC1 (1.00) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846737-B2 | Compound | STERIX LIMITED (GB) | 2014-09-30 | — | — | US | disclosed |
| US-20120238550-A1 | COMPOUND | UNIVERSITY OF BATH (GB) | 2012-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238550-A1 | COMPOUND | OXSR1, OXER1, CBR1 | GAA 4856/4885POLB 3831/4885HPGD 2270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.