Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5310267 | 0.79 | GAA (0.59) | POLBGAAKDM4EMEN1KMT2A | |
| SCHEMBL3669949 | 0.73 | AMY1A (0.65) | POLBGAAKDM4ECYP1A2CYP2C9 | |
| SCHEMBL3669947 | 0.73 | AMY1A (0.65) | POLBGAAKDM4ECYP1A2CYP2C9 | |
| SCHEMBL9821551 | 0.69 | POLB (0.48) | POLBGAAKDM4ECYP2C9CYP2C19 | |
| SCHEMBL9821549 | 0.69 | POLB (0.48) | POLBGAAKDM4ECYP2C9CYP2C19 | |
| SCHEMBL5873306 | 0.68 | CYP1A2 (0.56) | POLBGAAKDM4ECYP1A2CYP2C9 | |
| SCHEMBL14276077 | 0.68 | CYP1A2 (0.56) | POLBGAAKDM4ECYP1A2CYP2C9 | |
| SCHEMBL9821379 | 0.67 | GAA (0.60) | POLBGAAKDM4EALDH1A1HPGD | |
| SCHEMBL12450311 | 0.67 | GAA (0.60) | POLBGAAKDM4EALDH1A1HPGD | |
| SCHEMBL9821376 | 0.67 | GAA (0.60) | POLBGAAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008013986-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OPHTHALMIC LIGHT TOXICITY | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-01-31 | — | — | WO | disclosed |