Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1242805 | 0.75 | KDM4E (0.37) | KDM4EUSP2 | |
| SCHEMBL3879033 | 0.75 | SMN1; SMN2 (0.36) | HPGDALDH1A1LMNATP53HTT | |
| SCHEMBL1245101 | 0.75 | ADRB1 (0.42) | LMNAHTTMEN1KMT2A | |
| SCHEMBL15662928 | 0.74 | HPGD (0.66) | HPGDANPEPALDH1A1KDM4EMAPT | |
| SCHEMBL1244447 | 0.74 | LMNA (0.40) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL12346622 | 0.74 | HPGD (0.54) | HPGDANPEPALDH1A1KDM4EMAPT | |
| SCHEMBL1244423 | 0.72 | KDM4E (0.34) | KDM4EUSP2 | |
| SCHEMBL1244276 | 0.72 | TDP1 (0.38) | HPGDALDH1A1LMNATDP1 | |
| SCHEMBL1245437 | 0.71 | KDM4E (0.33) | KDM4EMAPTHTTUSP2MEN1 | |
| SCHEMBL12621160 | 0.70 | USP2 (0.40) | HTTTDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124545-B1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-02 | — | — | EP | disclosed |
| EP-2124545-B1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-02 | — | — | EP | disclosed |
| US-8569385-B2 | Hydrolysis resistant organomodified silylated ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8569385-B2 | Hydrolysis resistant organomodified silylated ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20110105428-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-05-05 | — | — | US | disclosed |
| US-7879916-B2 | Anionic, cationic or zwitterionic disilane surfactants; stable over a wide pH range; for controlling wetting, spreading, foaming, and detergency on applied surfaces; aqueous solutions improve delivery of active ingredients | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-7879916-B2 | Anionic, cationic or zwitterionic disilane surfactants; stable over a wide pH range; for controlling wetting, spreading, foaming, and detergency on applied surfaces; aqueous solutions improve delivery of active ingredients | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-02-01 | — | — | US | disclosed |
| EP-2124545-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | Momentive Performance Materials Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| EP-2124544-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | Momentive Performance Materials Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| US-20080167389-A1 | Hydrolysis resistant organomodified silylated ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-07-10 | — | — | US | disclosed |
| US-20080167389-A1 | Hydrolysis resistant organomodified silylated ionic surfactants | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-07-10 | — | — | US | disclosed |
| US-20080167269-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-07-10 | — | — | US | disclosed |
| US-20080167269-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-07-10 | — | — | US | disclosed |
| WO-2008073396-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008073397-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105428-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MLNR, SSTR3, FOXM1 | HPGD 3227/4885ANPEP 1212/4885ALDH1A1 2282/4885 |
| US-20080167389-A1 | Hydrolysis resistant organomodified silylated ionic surfactants | MLNR, SSTR3, FOXM1 | HPGD 3227/4885ANPEP 1212/4885ALDH1A1 2282/4885 |
| US-20080167269-A1 | HYDROLYSIS RESISTANT ORGANOMODIFIED SILYLATED IONIC SURFACTANTS | MLNR, SSTR3, FOXM1 | HPGD 3227/4885ANPEP 1212/4885ALDH1A1 2282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.