Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.57 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447398 | 0.91 | GAA (0.69) | RAB9ASLC22A6SLC22A8MEN1KMT2A | |
| SCHEMBL6060544 | 0.88 | HTT (0.61) | RAB9ASLC22A6SLC22A8MEN1KMT2A | |
| SCHEMBL30504089 | 0.84 | SLC22A6 (0.57) | RAB9ASLC22A6SLC22A8MEN1KMT2A | |
| SCHEMBL2049829 | 0.82 | KMT2A (0.55) | RAB9ASLC22A6SLC22A8MEN1KMT2A | |
| SCHEMBL15540877 | 0.81 | GAA (0.69) | MEN1KMT2ANFKB1ALDH1A1GAA | |
| SCHEMBL28524422 | 0.81 | PTPN7 (0.53) | RAB9ASLC22A6SLC22A8MEN1KMT2A | |
| SCHEMBL30504071 | 0.81 | GAA (0.63) | RAB9ASLC22A6SLC22A8MEN1KMT2A | |
| SCHEMBL4475231 | 0.80 | NPC1 (0.56) | RAB9AMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL597343 | 0.79 | ALOX5 (0.65) | SLC22A6SLC22A8MEN1KMT2ANFKB1 | |
| SCHEMBL30358985 | 0.79 | ALOX5 (0.65) | SLC22A6SLC22A8MEN1KMT2ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386211-B1 | USE OF RUBUSOSIDE TO REDUCE OR SUPPRESS PARTICULAR UNPLEASANT TASTE SENSATIONS | SYMRISE AG (DE) | 2016-08-10 | — | — | EP | claimed |
| EP-2386211-A1 | Use of rubusoside to reduce or suppress particular unpleasant taste sensations | Symrise AG (DE) | 2011-11-16 | — | — | EP | claimed |
| US-8041053-B2 | Vehicular sound effect generating apparatus | HONDA MOTOR CO., LTD. (JP) | 2011-10-18 | — | — | US | claimed |
| US-10165791-B2 | Use of rubusoside for reducing or suppressing certain unpleasant taste impressions | SYMRISE AG (DE) | 2019-01-01 | — | — | US | disclosed |
| US-20180070620-A1 | USE OF RUBUSOSIDE FOR REDUCING OR SUPPRESSING CERTAIN UNPLEASANT TASTE IMPRESSIONS | SYMRISE AG (DE) | 2018-03-15 | — | — | US | disclosed |
| EP-2292224-B1 | Derivatives of lactiosole for preventing or treating diabetes | SYMRISE AG (DE) | 2018-03-07 | — | — | EP | disclosed |
| US-9848624-B2 | Use of rubusoside for reducing or suppressing certain unpleasant taste impressions | SYMRISE AG (DE) | 2017-12-26 | — | — | US | disclosed |
| EP-2386211-B1 | USE OF RUBUSOSIDE TO REDUCE OR SUPPRESS PARTICULAR UNPLEASANT TASTE SENSATIONS | SYMRISE AG (DE) | 2016-08-10 | — | — | EP | disclosed |
| US-20140287122-A1 | USE OF RUBUSOSIDE FOR REDUCING OR SUPPRESSING CERTAIN UNPLEASANT TASTE IMPRESSIONS | SYMRISE AG (DE) | 2014-09-25 | — | — | US | disclosed |
| US-8592621-B2 | Precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease | SYMRISE AG (DE) | 2013-11-26 | — | — | US | disclosed |
| EP-2386211-A1 | Use of rubusoside to reduce or suppress particular unpleasant taste sensations | Symrise AG (DE) | 2011-11-16 | — | — | EP | disclosed |
| US-8041053-B2 | Vehicular sound effect generating apparatus | HONDA MOTOR CO., LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| EP-2292224-A1 | Precursor compounds of sweet receptor antagonists for preventing or treating diabetes | Symrise AG (DE) | 2011-03-09 | — | — | EP | disclosed |
| US-20110045069-A1 | PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE | SYMRISE GMBH CO. KG (DE) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110045069-A1 | PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE | TAS1R2, TAS2R5, TAS2R1 | RAB9A 1633/4885SLC22A6 748/4885SLC22A8 1383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.