Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 6/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.42 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11504878 | 0.84 | ALDH1A1 (0.50) | CYP2C19CYP2C9CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL29897548 | 0.84 | SMN1; SMN2 (0.50) | CYP2C19CYP2C9CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL27944723 | 0.84 | SMN1; SMN2 (0.50) | CYP2C19CYP2C9CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2294654 | 0.82 | CYP2C19 (0.48) | CYP2C19CYP2C9CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL15038850 | 0.80 | SMN1; SMN2 (0.56) | CYP2C19CYP2C9CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL11341071 | 0.79 | CYP2C19 (0.56) | CYP2C19CYP2C9CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL1524288 | 0.77 | SMN1; SMN2 (0.54) | CYP2C19CYP2C9CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL29410024 | 0.77 | SMN1; SMN2 (0.54) | CYP2C19CYP2C9CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL29410034 | 0.77 | SMN1; SMN2 (0.54) | CYP2C19CYP2C9CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL16383545 | 0.76 | SMN1; SMN2 (0.58) | CYP2C19CYP2C9CYP1A2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467958-B1 | PROCESS FOR PREPARING 3,3',5,5',6,6'-HEXAALKYL-2,2'-BIPHENOLS, 3,3',4,4',5,5'-HEXAALKYL-2,2'-BIPHENOLS AND 3,3',4,4',5,5',6,6'-OCTAALKYL-2,2'-BIPHENOLS | INVISTA TECH SARL (CH) | 2014-01-08 | — | — | EP | disclosed |
| EP-2279993-A1 | Process for preparing 3,3',5,5',6,6'-hexaalkyl-2,2'-biphenols, 3,3',4,4',5,5'-hexaalkyl-2,2'-biphenols and 3,3',4,4',5,5',6,6'-octaalkyl-2,2'-biphenols | INVISTA Technologies S.à.r.l. (CH) | 2011-02-02 | — | — | EP | disclosed |
| EP-1448503-B1 | PROCESS FOR PREPARING 3,3',6,6'-TETRAALKYL-2,2'-BIPHENOLS AND 3,3',6,6'-TETRAALKYL-5,5'-DIHALO-2,2'-BIPHENOLS | INVISTA TECH SARL (US) | 2008-01-30 | — | — | EP | disclosed |
| US-20040049087-A1 | Process for preparing 3,3',6,6'-tetraalkyl-2,2'-biphenols and 3,3',6,6'-tetraalkyl-5,5'-dihalo-2,2'-biphenols | INVISTA NORTH AMERICA S.A.R.L. (F/K/A ARTEVA NORTH AMERICA S.A.R.L.) | 2004-03-11 | — | — | US | disclosed |
| US-20030100802-A1 | Process for preparing 3,3',5,5',6,6'-hexaalkyl-2,2'-biphenols,3,3',4,4',5,5'-hexaalkyl-2,2'-biphenols and 3,3',4,4',5,5',6,6'-octaalkyl-2,2'-biphenols | SHAPIRO RAFAEL (US) | 2003-05-29 | — | — | US | disclosed |
| US-6555718-B1 | Oxidatively coupling of phenols in presence of Lewis Acid catalysts | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-04-29 | — | — | US | disclosed |
| US-6489517-B1 | CHLORINATING DIALKYLPHENOL, OXIDATIVELY COUPLING PRODUCT IN POLAR APROTIC SOLVENT TO PRODUCE DICHLOROTETRAALKYLBIPHENOL, DECHLORINATING TO PRODUCE TETRAALKYLBIPHENOL, BROMINATING OR IODINATING IF DESIRED | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100802-A1 | Process for preparing 3,3',5,5',6,6'-hexaalkyl-2,2'-biphenols,3,3',4,4',5,5'-hexaalkyl-2,2'-biphenols and 3,3',4,4',5,5',6,6'-octaalkyl-2,2'-biphenols | CYP4B1, UGT1A4, CYP4X1 | CYP2C19 83/4885CYP2C9 71/4885CYP1A2 44/4885 |
| US-20040049087-A1 | Process for preparing 3,3',6,6'-tetraalkyl-2,2'-biphenols and 3,3',6,6'-tetraalkyl-5,5'-dihalo-2,2'-biphenols | CYP2B6, CYP26B1, UGT1A6 | CYP2C19 80/4885CYP2C9 131/4885CYP1A2 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.