Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TYR | P14679 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.42 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11504878 | 0.84 | ALDH1A1 (0.50) | CYP2C19CYP2C9CYP1A2SMN1; SMN2CA2 | |
| SCHEMBL27944723 | 0.84 | SMN1; SMN2 (0.50) | CYP2C19CYP2C9CYP1A2SMN1; SMN2CA2 | |
| SCHEMBL29897548 | 0.84 | SMN1; SMN2 (0.50) | CYP2C19CYP2C9CYP1A2SMN1; SMN2CA2 | |
| SCHEMBL21409658 | 0.83 | CYP2C9 (0.39) | CYP2C19CYP2C9CYP1A2SMN1; SMN2CA2 | |
| SCHEMBL1524288 | 0.82 | SMN1; SMN2 (0.54) | CYP2C19CYP2C9CYP1A2SMN1; SMN2CA2 | |
| SCHEMBL29410034 | 0.82 | SMN1; SMN2 (0.54) | CYP2C19CYP2C9CYP1A2SMN1; SMN2CA2 | |
| SCHEMBL1245154 | 0.82 | CYP2C19 (0.48) | CYP2C19CYP2C9CYP1A2SMN1; SMN2CA2 | |
| SCHEMBL29410024 | 0.82 | SMN1; SMN2 (0.54) | CYP2C19CYP2C9CYP1A2SMN1; SMN2CA2 | |
| SCHEMBL29162188 | 0.80 | CYP2C19 (0.47) | CYP2C19CYP2C9CYP1A2SMN1; SMN2CA2 | |
| Selenium SCHEMBL30065154 | 0.80 | SMN1; SMN2 (0.52) | CYP2C19CYP2C9CYP1A2SMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9517986-B2 | Process for preparing 2,2′-biphenols using selenium dioxide | EVONIK DEGUSSA GMBH (DE) | 2016-12-13 | — | — | US | claimed |
| US-20150336865-A1 | PROCESS FOR PREPARING 2,2'-BIPHENOLS USING SELENIUM DIOXIDE | EVONIK DEGUSSA GMBH (DE) | 2015-11-26 | — | — | US | claimed |
| EP-3023430-B1 | TRANSITION METAL/CARBENE COMPLEX AND PROCESS FOR PRODUCING SAME | ZEON CORP (JP) | 2018-01-31 | — | — | EP | disclosed |
| EP-2949638-B1 | METHOD FOR THE PREPARATION OF 2,2 -BIPHENOLS USING SELENIUM DIOXIDE | EVONIK DEGUSSA GMBH (DE) | 2017-11-08 | — | — | EP | disclosed |
| US-9701701-B2 | Transition metal carbene complex and method of producing the same | ZEON CORPORATION (JP) | 2017-07-11 | — | — | US | disclosed |
| US-9550800-B2 | — | — | 2017-01-24 | — | — | US | disclosed |
| US-9517986-B2 | Process for preparing 2,2′-biphenols using selenium dioxide | EVONIK DEGUSSA GMBH (DE) | 2016-12-13 | — | — | US | disclosed |
| US-20160152645-A1 | TRANSITION METAL CARBENE COMPLEX AND METHOD OF PRODUCING THE SAME | ZEON CORPORATION (JP) | 2016-06-02 | — | — | US | disclosed |
| EP-3023430-A1 | TRANSITION METAL/CARBENE COMPLEX AND PROCESS FOR PRODUCING SAME | Zeon Corporation (JP) | 2016-05-25 | — | — | EP | disclosed |
| EP-2949638-A1 | METHOD FOR THE PREPARATION OF 2,2 -BIPHENOLS USING SELENIUM DIOXIDE | Evonik Degussa GmbH (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-20150336865-A1 | PROCESS FOR PREPARING 2,2'-BIPHENOLS USING SELENIUM DIOXIDE | EVONIK DEGUSSA GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| EP-2346887-B1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2013-12-25 | — | — | EP | disclosed |
| US-8546600-B2 | Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite | DOW TECHNOLOGY INVESTMENTS LLC | 2013-10-01 | — | — | US | disclosed |
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | DOW TECHNOLOGY INVESTMENTS LLC | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152645-A1 | TRANSITION METAL CARBENE COMPLEX AND METHOD OF PRODUCING THE SAME | C5, CYC1, C1S | CYP2C19 97/4885CYP2C9 277/4885CYP1A2 77/4885 |
| US-20150336865-A1 | PROCESS FOR PREPARING 2,2'-BIPHENOLS USING SELENIUM DIOXIDE | SELENOI, PLK1, BPGM | CYP2C19 514/4885CYP2C9 1044/4885CYP1A2 336/4885 |
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | SOST, PLCB3, PPIP5K2 | CYP2C19 2320/4885CYP2C9 1721/4885CYP1A2 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.