SCHEMBL16383545

SCHEMBL16383545

Cc1c(C(C)(C)C)cc(C(C)(C)C)c(O)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.58
ALDH1A1 P00352 6/20 0.58
CA2 P00918 4/20 0.58
POLB P06746 1/20 0.58
TYR P14679 1/20 0.58
CA1 P00915 2/20 0.54
CYP2C9 P11712 4/20 0.52
CYP2C19 P33261 4/20 0.52
CYP1A2 P05177 4/20 0.52
GLRA3 O75311 1/20 0.50
GLRB P48167 1/20 0.50
HIF1A Q16665 4/20 0.47
TP53 P04637 2/20 0.47
HSPA5 P11021 1/20 0.47
ALOX15 P16050 3/20 0.46
MAPT P10636 3/20 0.46
HPN P05981 1/20 0.46
SIRT5 Q9NXA8 1/20 0.46
KDM4E B2RXH2 1/20 0.46
ATP2A2 P16615 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15038850 0.90 SMN1; SMN2 (0.56) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL8657615 0.85 SMN1; SMN2 (0.58) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL9244593 0.84 SMN1; SMN2 (0.64) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL20657093 0.84 CA2 (0.65) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL6757169 0.83 SMN1; SMN2 (0.56) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL29897548 0.83 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL2221169 0.83 ALDH1A1 (0.56) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL31108090 0.83 SMN1; SMN2 (0.56) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL27944723 0.83 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL13400274 0.81 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3063234-B1 RED THERMOCHROMIC DYES AND THEIR INK COMPOSITIONS CHROMATIC TECH INC (US) 2018-06-27 EP disclosed
US-9745487-B2 Yellow thermochromic dyes, inks composition and level indicators CHROMATIC TECHNOLOGIES, INC. (US) 2017-08-29 US disclosed
US-9745487-B2 Yellow thermochromic dyes, inks composition and level indicators CHROMATIC TECHNOLOGIES, INC. (US) 2017-08-29 US disclosed
EP-3017010-B1 YELLOW THERMOCHROMIC DYES, INKS COMPOSITION AND LEVEL INDICATORS CHROMATIC TECH INC (US) 2017-05-17 EP disclosed
US-9580603-B2 Red thermochromic dyes and their ink compositions CHROMATIC TECHNOLOGIES, INC. (US) 2017-02-28 US disclosed
US-9580603-B2 Red thermochromic dyes and their ink compositions CHROMATIC TECHNOLOGIES, INC. (US) 2017-02-28 US disclosed
US-20160333210-A1 Yellow Thermochromic Dyes, Inks Composition And Level Indicators CHROMATIC TECHNOLOGIES, INC. (US) 2016-11-17 US disclosed
US-20160333210-A1 Yellow Thermochromic Dyes, Inks Composition And Level Indicators CHROMATIC TECHNOLOGIES, INC. (US) 2016-11-17 US disclosed
US-9399716-B2 Yellow thermochromic dyes, inks composition and level indicators CHROMATIC TECHNOLOGIES INC. (US) 2016-07-26 US disclosed
US-9399716-B2 Yellow thermochromic dyes, inks composition and level indicators CHROMATIC TECHNOLOGIES INC. (US) 2016-07-26 US disclosed
WO-2015048536-A1 RED THERMOCHROMIC DYES AND THEIR INK COMPOSITIONS CHROMATIC TECHNOLOGIES INC. (US) 2015-04-02 WO disclosed
US-20150090159-A1 RED THERMOCHROMIC DYES AND THEIR INK COMPOSITIONS CHROMATIC TECHNOLOGIES, INC. 2015-04-02 US disclosed
WO-2015003046-A1 YELLOW THERMOCHROMIC DYES, INKS COMPOSITION AND LEVEL INDICATORS CHROMATIC TECHNOLOGIES INC. (US) 2015-01-08 WO disclosed