SCHEMBL1245170

SCHEMBL1245170

COc1ccc(C2CCc3ccc(O)cc3O2)cc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 4/20 0.67
ESR1 P03372 3/20 0.67
CYP19A1 P11511 3/20 0.55
TP53 P04637 2/20 0.55
CYP3A4 P08684 2/20 0.55
XDH P47989 2/20 0.55
CYP1A1 P04798 2/20 0.55
CYP1A2 P05177 2/20 0.55
CYP1B1 Q16678 2/20 0.55
MAPT P10636 1/20 0.55
HPGD P15428 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PKM P14618 1/20 0.55
NPC1 O15118 1/20 0.55
CA12 O43570 1/20 0.55
KDM1A O60341 1/20 0.55
ALDH1A1 P00352 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
TSHR P16473 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30475350 1.00 ESR2 (0.67) ESR2ESR1CYP19A1TP53CYP3A4
SCHEMBL2958816 1.00 ESR2 (0.67) ESR2ESR1CYP19A1TP53CYP3A4
SCHEMBL1487483 1.00 ESR2 (0.67) ESR2ESR1CYP19A1TP53CYP3A4
SCHEMBL30233728 1.00 ESR2 (0.67) ESR2ESR1CYP19A1TP53CYP3A4
SCHEMBL3693283 0.90 ESR1 (0.67) ESR2ESR1CYP19A1CYP1A1CYP1A2
SCHEMBL3693175 0.90 ESR1 (0.67) ESR2ESR1CYP19A1CYP1A1CYP1A2
SCHEMBL2964362 0.89 CYP19A1 (0.61) ESR2ESR1CYP19A1TP53CYP3A4
SCHEMBL31527713 0.86 CYP19A1 (0.53) ESR2ESR1CYP19A1TP53CYP3A4
SCHEMBL27182775 0.86 CYP19A1 (0.53) ESR2ESR1CYP19A1TP53CYP3A4
SCHEMBL669209 0.85 ESR2 (0.66) ESR2ESR1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US claimed
EP-4482306-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-01 EP claimed
WO-2023192424-A1 VOLATILE HD AC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS CROSS-REFERENCE TO RELATED APPLICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-05 WO claimed
US-10869493-B2 Reduced-sweetener products, flavoring mixtures for said reduced-sweetener products and process for the production of products of this type SYMRISE AG (DE) 2020-12-22 US claimed
US-20200205445-A1 REDUCED-SWEETENER PRODUCTS, FLAVORING MIXTURES FOR SAID REDUCED-SWEETENER PRODUCTS AND PROCESS FOR THE PRODUCTION OF PRODUCTS OF THIS TYPE SYMRISE AG (DE) 2020-07-02 US claimed
US-10624372-B2 Reduced-sweetener products, flavoring mixtures for said reduced-sweetener products and process for the production of products of this type SYMRISE AG (DE) 2020-04-21 US claimed
EP-2386211-B1 USE OF RUBUSOSIDE TO REDUCE OR SUPPRESS PARTICULAR UNPLEASANT TASTE SENSATIONS SYMRISE AG (DE) 2016-08-10 EP claimed
EP-2253226-B1 Use of hydroxyflavone derivatives for modifying taste LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) 2015-07-15 EP claimed
US-20140287122-A1 USE OF RUBUSOSIDE FOR REDUCING OR SUPPRESSING CERTAIN UNPLEASANT TASTE IMPRESSIONS SYMRISE AG (DE) 2014-09-25 US claimed
EP-2559346-B1 Oleanene-type triterpene glycosides as masking agents SYMRISE AG (DE) 2014-03-26 EP claimed
WO-2013023891-A1 OLEANENE-TYPE TRITERPENE GLYCOSIDES AS MASKING AGENTS SYMRISE AG (DE) 2013-02-21 WO claimed
EP-2559346-A1 Oleanene-type triterpene glycosides as masking agents Symrise AG (DE) 2013-02-20 EP claimed
EP-2386211-A1 Use of rubusoside to reduce or suppress particular unpleasant taste sensations Symrise AG (DE) 2011-11-16 EP claimed
EP-2298084-B1 Sweetener-reduced products, aromatic mixtures for same and method of producing such products SYMRISE AG (DE) 2011-10-19 EP claimed
US-8041053-B2 Vehicular sound effect generating apparatus HONDA MOTOR CO., LTD. (JP) 2011-10-18 US claimed
US-20110076239-A1 REDUCED-SWEETENER PRODUCTS, FLAVORING MIXTURES FOR SAID REDUCED-SWEETENER PRODUCTS AND PROCESS FOR THE PRODUCTION OF PRODUCTS OF THIS TYPE SYMRISE AG (DE) 2011-03-31 US claimed
EP-2253226-A1 Use of hydroxyflavone derivatives for modifying taste Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) 2010-11-24 EP claimed
US-20100292175-A1 USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION Leibniz-Institut fur Pflanzenbiochemie (DE) 2010-11-18 US claimed
US-20260033524-A1 FLAVOR MODIFYING COMPOSITIONS CORN PRODUCTS DEV INC (US) 2026-02-05 US disclosed
US-20100292175-A1 USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION Leibniz-Institut fur Pflanzenbiochemie (DE) 2010-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200205445-A1 REDUCED-SWEETENER PRODUCTS, FLAVORING MIXTURES FOR SAID REDUCED-SWEETENER PRODUCTS AND PROCESS FOR THE PRODUCTION OF PRODUCTS OF THIS TYPE SORD, TAS2R40, TAS2R30 ESR2 3469/4885ESR1 4012/4885CYP19A1 4749/4885
US-10624372-B2 Reduced-sweetener products, flavoring mixtures for said reduced-sweetener products and process for the production of products of this type SORD, TAS2R40, TAS2R30 ESR2 3469/4885ESR1 4012/4885CYP19A1 4749/4885
US-20260033524-A1 FLAVOR MODIFYING COMPOSITIONS TAS2R42, TAS2R7, TAS2R31 ESR2 3113/4885ESR1 4619/4885CYP19A1 4092/4885
US-10869493-B2 Reduced-sweetener products, flavoring mixtures for said reduced-sweetener products and process for the production of products of this type SORD, TAS2R40, TAS2R30 ESR2 3469/4885ESR1 4012/4885CYP19A1 4749/4885
US-20110076239-A1 REDUCED-SWEETENER PRODUCTS, FLAVORING MIXTURES FOR SAID REDUCED-SWEETENER PRODUCTS AND PROCESS FOR THE PRODUCTION OF PRODUCTS OF THIS TYPE TAS2R30, TAS2R40, TAS2R60 ESR2 3184/4885ESR1 4285/4885CYP19A1 4783/4885
US-20100292175-A1 USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION TAS2R50, TAS2R60, TAS2R30 ESR2 2632/4885ESR1 3623/4885CYP19A1 3419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.