Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12458153 | 0.95 | MGLL (0.52) | MGLLFAAHHSP90AA1TLR9ALDH1A1 | |
| SCHEMBL16675656 | 0.94 | MGLL (0.39) | MGLLFAAHHSP90AA1TLR9ALDH1A1 | |
| SCHEMBL835434 | 0.90 | CYP19A1 (0.39) | ALDH1A1LMNAPKMMAPK1HTT | |
| SCHEMBL24520484 | 0.85 | MGLL (0.56) | MGLLFAAHHSP90AA1TLR9ALDH1A1 | |
| SCHEMBL19601273 | 0.83 | POLB (0.39) | ALDH1A1LMNAPKMMAPK1HTT | |
| SCHEMBL14328060 | 0.82 | CYP19A1 (0.49) | MGLLALDH1A1PKMSMN1; SMN2CYP19A1 | |
| SCHEMBL16867177 | 0.81 | CYP19A1 (0.50) | MGLLFAAHALDH1A1SMN1; SMN2PTGS1 | |
| SCHEMBL14327735 | 0.81 | LMNA (0.37) | ALDH1A1LMNAPKMMAPK1HTT | |
| SCHEMBL20634216 | 0.79 | CYP19A1 (0.51) | MGLLFAAHSMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL15431909 | 0.79 | CYP19A1 (0.37) | ALDH1A1LMNAPKMMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037659-A1 | METHODS OF PREPARATION OF CONJUGATES | IMMUNOGEN, INC. | 2018-02-08 | — | — | US | disclosed |
| US-9868791-B2 | Methods of preparation of conjugates | IMMUNOGEN, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| US-20160324980-A1 | METHODS OF PREPARATION OF CONJUGATES | IMMUNOGEN, INC. | 2016-11-10 | — | — | US | disclosed |
| US-9353127-B2 | Methods of preparation of conjugates | IMMUNOGEN, INC. (US) | 2016-05-31 | — | — | US | disclosed |
| US-20120238731-A1 | METHODS OF PREPARATION OF CONJUGATES | IMMUNOGEN, INC. (US) | 2012-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238731-A1 | METHODS OF PREPARATION OF CONJUGATES | MCL1, EPCAM, PAICS | MGLL 4708/4885FAAH 4586/4885HSP90AA1 2082/4885 |
| US-20160324980-A1 | METHODS OF PREPARATION OF CONJUGATES | MCL1, EPCAM, PAICS | MGLL 4708/4885FAAH 4586/4885HSP90AA1 2082/4885 |
| US-20180037659-A1 | METHODS OF PREPARATION OF CONJUGATES | MCL1, EPCAM, PAICS | MGLL 4708/4885FAAH 4586/4885HSP90AA1 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.