Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17920552 | 0.91 | MGLL (0.39) | MGLLPOLBLMNATSHRALDH1A1 | |
| SCHEMBL16675656 | 0.88 | MGLL (0.39) | MGLLPOLBFAAHLMNAALDH1A1 | |
| SCHEMBL25892775 | 0.86 | MGLL (0.35) | MGLLPOLBLMNATSHRALDH1A1 | |
| SCHEMBL12458152 | 0.85 | MGLL (0.46) | MGLLPOLBFAAHLMNAALDH1A1 | |
| SCHEMBL26878187 | 0.84 | POLB (0.34) | MGLLPOLBLMNATSHRALDH1A1 | |
| SCHEMBL17921780 | 0.84 | POLB (0.34) | MGLLPOLBLMNATSHRALDH1A1 | |
| SCHEMBL25868159 | 0.84 | POLB (0.34) | MGLLPOLBLMNATSHRALDH1A1 | |
| SCHEMBL4741521 | 0.84 | LMNA (0.38) | MGLLPOLBLMNATSHRALDH1A1 | |
| SCHEMBL25868269 | 0.84 | POLB (0.34) | MGLLPOLBLMNATSHRALDH1A1 | |
| SCHEMBL26878191 | 0.84 | POLB (0.34) | MGLLPOLBLMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362100-B1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH INC (US) | 2022-06-22 | — | — | EP | disclosed |