Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15302509 | 0.90 | POLB (0.44) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL10580556 | 0.87 | THRB (0.50) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL15302556 | 0.86 | KDM4E (0.45) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL12458557 | 0.85 | TDP1 (0.43) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL29791122 | 0.85 | KDM4E (0.54) | POLBTDP1APEX1HTTALDH1A1 | |
| SCHEMBL2033345 | 0.85 | KDM4E (0.54) | POLBTDP1APEX1HTTALDH1A1 | |
| SCHEMBL10398142 | 0.84 | MAPT (0.44) | POLBTDP1APEX1HTTTHRB | |
| SCHEMBL2033775 | 0.84 | KDM4E (0.58) | TDP1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL29791099 | 0.84 | KDM4E (0.58) | TDP1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL12458556 | 0.83 | THRB (0.44) | POLBTDP1APEX1HTTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8900479-B2 | Liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2014-12-02 | — | — | US | disclosed |
| US-8900479-B2 | Liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2014-12-02 | — | — | US | disclosed |
| US-20120236246-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2012-09-20 | — | — | US | disclosed |
| US-20120236246-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2012-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120236246-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | LASP1, VCL, NLK | POLB 3994/4885TDP1 3020/4885APEX1 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.