Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12446624 | 0.90 | KDM4E (0.46) | KDM4EALDH1A1HPGDPTGS2 | |
| SCHEMBL12458553 | 0.88 | KDM4E (0.42) | MAPTKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL15302509 | 0.86 | POLB (0.44) | MAPTKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL29791099 | 0.86 | KDM4E (0.58) | KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL2033775 | 0.86 | KDM4E (0.58) | KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL12458558 | 0.84 | POLB (0.47) | MAPTKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL12416580 | 0.82 | NR2E1 (0.45) | KDM4EALDH1A1HPGDTDP1APEX1 | |
| SCHEMBL12458557 | 0.82 | TDP1 (0.43) | MAPTKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL9880797 | 0.82 | MTNR1A (0.47) | MAPTKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL17148019 | 0.81 | MAPT (0.47) | MAPTKDM4EALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906713-A | \"Acrylic\" ladder polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | claimed |
| US-20110171609-A1 | Dental Composition Comprising Biphenyl Di(meth)acrylate Monomer | 3M INNOVATIVE PROPERTIES COMPANY | 2011-07-14 | — | — | US | disclosed |
| US-20110171609-A1 | Dental Composition Comprising Biphenyl Di(meth)acrylate Monomer | 3M INNOVATIVE PROPERTIES COMPANY | 2011-07-14 | — | — | US | disclosed |
| WO-2010027676-A2 | DENTAL COMPOSITION COMPRISING BIPHENYL DI(METH)ACRYLATE MONOMER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-03-11 | — | — | WO | disclosed |
| US-4906713-A | \"Acrylic\" ladder polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-06 | — | — | US | disclosed |