SCHEMBL2033775

SCHEMBL2033775

C=C(C)C(=O)OCCOc1cccc2ccccc12

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.58
ALDH1A1 P00352 4/20 0.58
HPGD P15428 3/20 0.58
TDP1 Q9NUW8 1/20 0.51
HTR1B P28222 7/20 0.50
HTR1D P28221 1/20 0.50
MCL1 Q07820 2/20 0.49
BCL2 P10415 1/20 0.49
BCL2L1 Q07817 1/20 0.49
BAD Q92934 1/20 0.49
SLC6A4 P31645 2/20 0.49
HRH1 P35367 1/20 0.49
ATM Q13315 1/20 0.48
TSHR P16473 1/20 0.48
KCNA3 P22001 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
OGG1 O15527 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29791099 1.00 KDM4E (0.58) KDM4EALDH1A1HPGDTDP1HTR1B
SCHEMBL10605986 0.93 KDM4E (0.57) KDM4EALDH1A1HPGDTDP1HTR1B
SCHEMBL1806256 0.92 KDM4E (0.56) KDM4EALDH1A1HPGDTDP1HTR1B
SCHEMBL1803976 0.92 KDM4E (0.56) KDM4EALDH1A1HPGDTDP1HTR1B
SCHEMBL10871016 0.91 THRB (0.46) KDM4EALDH1A1HPGDTDP1HTR1B
SCHEMBL5066187 0.88 KDM4E (0.47) KDM4EALDH1A1HPGDTDP1HTR1B
SCHEMBL15302556 0.88 KDM4E (0.45) KDM4EALDH1A1HPGDTDP1HTR1B
SCHEMBL10580556 0.86 THRB (0.50) KDM4EALDH1A1TDP1TSHRKMT2A
SCHEMBL10398142 0.86 MAPT (0.44) KDM4EALDH1A1HPGDTDP1
SCHEMBL15302509 0.86 POLB (0.44) KDM4EALDH1A1HPGDTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101981477-B Adhesive layer for multilayer optical film 3M INNOVATIVE PROPERTIES CO 2012-10-10 CN claimed
CN-101981477-A Adhesive layer for multilayer optical film 3M INNOVATIVE PROPERTIES CO 2011-02-23 CN claimed
CN-116723831-A Emulsion comprising size-controlled droplets 卡莉西亚公司 2023-09-08 CN disclosed
CN-111533668-A Cyanostilbenes 罗利克技术有限公司 2020-08-14 CN disclosed
CN-108138019-B pressure sensitive adhesive composition 株式会社LG化学 2019-10-11 CN disclosed
CN-110062769-A The method for preparing the particle and microcapsules of controlled dimensions 卡莉西亚公司 2019-07-26 CN disclosed
CN-110062779-A The method for preparing controlled dimensions microcapsules including photopolymerization step 卡莉西亚公司 2019-07-26 CN disclosed
US-10329486-B2 Cyanostilbenes ROLIC AG (CH) 2019-06-25 US disclosed
CN-109563390-A pressure sensitive adhesive composition 株式会社LG化学 2019-04-02 CN disclosed
CN-105778831-B Adhesive composition and adhesive film 藤森工业株式会社 2019-03-12 CN disclosed
CN-109207101-A Adhesion agent composition and adhesive film 藤森工业株式会社 2019-01-15 CN disclosed
EP-1928979-B1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS ROLIC AG (CH) 2009-03-04 EP disclosed
CN-101356452-A Resin composition for optical material, resin film for optical material, and optical waveguide HITACHI CHEMICAL CO LTD (JP) 2009-01-28 CN disclosed
US-20080274304-A1 Functionalized Photoreactive Compounds ROLIC AG (CH) 2008-11-06 US disclosed
CN-101268168-A Functionalized photoreactive compounds ROLIC AG (CH) 2008-09-17 CN disclosed
EP-1764405-A1 Functionalized photoreactive compounds Rolic AG (CH) 2007-03-21 EP disclosed
CN-1831984-A Protective film for optical disks and optical disk using the same LINTEC CORP (JP) 2006-09-13 CN disclosed
EP-0940694-B1 Photochromic curable composition TOKUYAMA CORP (JP) 2002-08-14 EP disclosed
US-6194511-B1 COMPRISING POLYMERIZABLE MONOMER CONTAINING SULFUR-CONTAINING (METH)ACRYLATE POLYMERIZABLE MONOMER AND PHOTOCHROMIC COMPOUND TOKUYAMA CORPORATION (JP) 2001-02-27 US disclosed
EP-0940694-A1 Photochromic curable composition TOKUYAMA CORPORATION (JP) 1999-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274304-A1 Functionalized Photoreactive Compounds PCNA, PIN1, MAP1LC3C KDM4E 2641/4885ALDH1A1 147/4885HPGD 1529/4885
US-10329486-B2 Cyanostilbenes LATS1, LATS2, CRY1 KDM4E 1611/4885ALDH1A1 2838/4885HPGD 4309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.