Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | HINT1 | P49773 | 2/20 | 0.44 |
| ▸ | GAPDH | P04406 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032731 | 1.00 | MEN1 (0.51) | MEN1USP2POLBKMT2AKDM4E | |
| SCHEMBL12582835 | 1.00 | MEN1 (0.51) | MEN1USP2POLBKMT2AKDM4E | |
| SCHEMBL29558174 | 0.89 | KDM4E (0.46) | MEN1USP2POLBKMT2AKDM4E | |
| SCHEMBL23827894 | 0.89 | KDM4E (0.46) | MEN1USP2POLBKMT2AKDM4E | |
| SCHEMBL29557868 | 0.89 | KDM4E (0.46) | MEN1USP2POLBKMT2AKDM4E | |
| SCHEMBL29558873 | 0.88 | TAS1R3 (0.45) | MEN1USP2POLBKMT2AKDM4E | |
| SCHEMBL29558193 | 0.88 | TAS1R3 (0.45) | MEN1USP2POLBKMT2AKDM4E | |
| SCHEMBL29558256 | 0.88 | TAS1R3 (0.45) | MEN1USP2POLBKMT2AKDM4E | |
| SCHEMBL12582838 | 0.86 | PNP (0.48) | KDM4ETAS1R3TAS1R1PNPGSK3A | |
| SCHEMBL22401432 | 0.86 | MEN1 (0.55) | MEN1USP2POLBKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103468-A2 | PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION | CHEMGENES CORPORATION (US) | 2011-08-25 | — | — | WO | disclosed |