Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | FLT1 | P17948 | 6/20 | 0.70 |
| ▸ | FLT4 | P35916 | 6/20 | 0.70 |
| ▸ | KDR | P35968 | 6/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12674392 | 0.87 | ALDH1A1 (0.59) | ALDH1A1FLT1FLT4KDRPOLB | |
| SCHEMBL12459531 | 0.87 | FLT1 (0.69) | ALDH1A1FLT1FLT4KDRPOLB | |
| SCHEMBL12674501 | 0.85 | FLT1 (0.56) | ALDH1A1FLT1FLT4KDRPOLB | |
| SCHEMBL12459304 | 0.84 | GAA (0.58) | ALDH1A1POLBHTTGAAMEN1 | |
| SCHEMBL12458726 | 0.84 | GAA (0.68) | ALDH1A1POLBHTTGAAMEN1 | |
| SCHEMBL10989349 | 0.84 | FLT1 (1.00) | FLT1FLT4KDRL3MBTL1PTGS1 | |
| SCHEMBL12459303 | 0.83 | FLT1 (0.64) | ALDH1A1FLT1FLT4KDRPOLB | |
| SCHEMBL2705461 | 0.81 | L3MBTL1 (0.83) | ALDH1A1POLBHTTL3MBTL1GAA | |
| SCHEMBL12459445 | 0.80 | ALDH1A1 (0.56) | ALDH1A1POLBHTTGAAMEN1 | |
| SCHEMBL12459449 | 0.80 | GAA (0.53) | ALDH1A1POLBHTTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011102514-A1 | AROMATIC RING COMPOUND | 武田薬品工業株式会社 (JP) | 2011-08-25 | — | — | WO | disclosed |