Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12459304 | 0.88 | GAA (0.58) | GAASMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL12459274 | 0.83 | EPHX2 (0.53) | GAASMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL12458726 | 0.82 | GAA (0.68) | GAASMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL12675242 | 0.81 | HTT (0.44) | GAASMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL12459286 | 0.80 | ALDH1A1 (0.75) | GAASMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL12675032 | 0.79 | MEN1 (0.51) | SMN1; SMN2POLBHTTALDH1A1TRPV4 | |
| SCHEMBL12459439 | 0.79 | TRPV4 (0.59) | GAASMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL12459303 | 0.77 | FLT1 (0.64) | GAASMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL12459445 | 0.76 | ALDH1A1 (0.56) | GAASMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL12674697 | 0.76 | MEN1 (0.53) | GAASMN1; SMN2POLBHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011102514-A1 | AROMATIC RING COMPOUND | 武田薬品工業株式会社 (JP) | 2011-08-25 | — | — | WO | disclosed |