SCHEMBL1245940

SCHEMBL1245940

Nc1ccc(-c2ccc(N)c(NO)c2)cc1NO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.48
HSD17B10 Q99714 2/20 0.48
ALOX15 P16050 1/20 0.48
KMT2A Q03164 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
MEN1 O00255 2/20 0.48
HDAC2 Q92769 13/20 0.47
HDAC3 O15379 5/20 0.47
HDAC1 Q13547 5/20 0.47
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
KDM4E B2RXH2 2/20 0.41
GFER P55789 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
MAPK1 P28482 2/20 0.41
ESR2 Q92731 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19511618 0.80 MAPT (0.40) CYP3A4HSD17B10ALOX15KMT2ATDP1
SCHEMBL29094347 0.78 CA14 (0.43) CYP3A4HSD17B10ALOX15KMT2ATDP1
SCHEMBL19005034 0.78 HDAC1 (0.55) HDAC2HDAC1
SCHEMBL19004965 0.77 DYRK1A (0.42) CYP3A4HSD17B10TDP1HDAC2ALDH1A1
SCHEMBL18576423 0.76 KDM4E (0.45) ALOX15KMT2AMEN1HDAC2HDAC1
SCHEMBL19005073 0.76 PIK3CD (0.52) HDAC2HDAC1ALDH1A1KDM4EMAPT
SCHEMBL19005173 0.75 KEAP1 (0.53) KMT2AHDAC2HDAC3HDAC1
SCHEMBL19511659 0.75 PTK2 (0.35) HSD17B10ALDH1A1KDM4EGFERMAPT
SCHEMBL5605835 0.75 CYP3A4 (0.48) CYP3A4HSD17B10ALOX15KMT2ATDP1
SCHEMBL8522276 0.75 LMNA (0.51) CYP3A4HSD17B10ALOX15KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2281926-B1 HOLLOW FIBER AND METHOD FOR MANUFACTURING A HOLLOW FIBER IUCF HYU (KR) 2018-09-05 EP disclosed
EP-2281926-A2 HOLLOW FIBER, DOPE SOLUTION COMPOSITION FOR FORMING A HOLLOW FIBER, AND METHOD FOR MANUFACTURING A HOLLOW FIBER USING THE SAME IUCF-HYU (Industry-University Cooperation Foundation Hanyang University) (KR) 2011-02-09 EP disclosed
US-20090297850-A1 HOLLOW FIBER, DOPE COMPOSITION FOR FORMING HOLLOW FIBER, AND METHOD OF MAKING HOLLOW FIBER USING THE SAME IUCF-HYU(INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2009-12-03 US disclosed