SCHEMBL1245952

SCHEMBL1245952

NCCNC(=O)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.64
TSHR P16473 1/20 0.64
NFKB1 P19838 1/20 0.64
MAOB P27338 1/20 0.64
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
BLM P54132 1/20 0.62
PMP22 Q01453 1/20 0.62
LMNA P02545 2/20 0.59
POLB P06746 1/20 0.59
HPGD P15428 2/20 0.58
ALDH1A1 P00352 1/20 0.58
SPHK2 Q9NRA0 1/20 0.56
GAA P10253 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.54
NPC1 O15118 3/20 0.53
RAB9A P51151 3/20 0.53
EPHX2 P34913 1/20 0.53
PRSS1 P07477 1/20 0.53
CTSG P08311 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL731620 0.93 CYP1A2 (0.67) CYP1A2TSHRNFKB1MAOBMEN1
Hydrochloric Acid SCHEMBL1579939 0.91 MEN1 (0.68) CYP1A2TSHRNFKB1MAOBMEN1
SCHEMBL12534688 0.90 NPC1 (0.58) CYP1A2TSHRNFKB1MAOBMEN1
SCHEMBL3861146 0.87 MAOB (0.81) CYP1A2TSHRNFKB1MAOBMEN1
SCHEMBL18759244 0.86 NPC1 (0.64) CYP1A2TSHRNFKB1MAOBMEN1
SCHEMBL1246967 0.84 LMNA (0.61) MEN1KMT2ALMNAPOLBHPGD
SCHEMBL22769214 0.83 SMN1; SMN2 (0.74) MEN1KMT2ALMNAPOLBHPGD
SCHEMBL1246757 0.83 HDAC3 (0.57) CYP1A2TSHRNFKB1MAOBMEN1
SCHEMBL17226037 0.82 NAAA (0.65) MEN1KMT2ALMNAPOLBHPGD
SCHEMBL6657326 0.82 HDAC2 (0.65) MEN1KMT2ALMNAPOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10252291-B2 Photo-curing of thermoplastic coatings COLOPLAST A/S (DK) 2019-04-09 US disclosed
EP-2394676-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2018-03-28 EP disclosed
US-20160355688-A1 Coating For A Surface GORE & ASS (US) 2016-12-08 US disclosed
US-9447304-B2 Coating for a surface W. L. GORE & ASSOCIATES, INC. (US) 2016-09-20 US disclosed
CN-103468108-B Coating composition COLOPLAST A/S (DK) 2016-03-02 CN disclosed
EP-2459242-B1 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST AS (DK) 2015-10-21 EP disclosed
EP-2104523-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2015-08-26 EP disclosed
US-8932662-B2 Coatings prepared from poly(ethylene oxide) and photo-initator-containing scaffolds COLOPLAST A/S (DK) 2015-01-13 US disclosed
EP-2049172-B1 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST AS (DK) 2014-12-31 EP disclosed
US-20140363562-A1 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST A/S (DK) 2014-12-11 US disclosed
US-20100049146-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2010-02-25 US disclosed
CN-101631576-A Coatings prepared from poly (ethylene oxide) and a photoinitiator-containing scaffold material COLOPLAST AS 2010-01-20 CN disclosed
EP-2104523-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS Coloplast A/S (DK) 2009-09-30 EP disclosed
CN-101495162-A Photocuring of thermoplastic coatings COLOPLAST AS (DK) 2009-07-29 CN disclosed
EP-2049172-A2 PHOTO-CURING OF THERMOPLASTIC COATINGS Coloplast A/S (DK) 2009-04-22 EP disclosed
WO-2008071796-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2008-06-19 WO disclosed
WO-2008012325-A2 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST A/S (DK) 2008-01-31 WO disclosed
EP-0000705-B1 USE OF ESTERS OR AMIDES OF BENZOYLBENZOIC ACIDS AS PHOTOINITIATORS AND PHOTOPOLYMERISABLE COMPOSITION CONTAINING THEM STAUFFER CHEMICAL COMPANY (US) 1981-02-11 EP disclosed
EP-0000705-A1 Use of esters or amides of benzoylbenzoic acids as photoinitiators and photopolymerisable composition containing them STAUFFER CHEMICAL COMPANY (US) 1979-02-21 EP disclosed
US-4080275-A POLYMERIZATION INITIATOR, ETHYLENICALLY UNSATURATED MONOMER STAUFFER CHEMICAL COMPANY (US) 1978-03-21 US disclosed