SCHEMBL1246967

SCHEMBL1246967

O=C(NCCO)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
POLB P06746 2/20 0.61
HPGD P15428 4/20 0.60
ALDH1A1 P00352 1/20 0.60
GAA P10253 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.55
SPHK2 Q9NRA0 1/20 0.55
SPHK1 Q9NYA1 1/20 0.55
NPC1 O15118 4/20 0.55
RAB9A P51151 4/20 0.55
EPHX2 P34913 1/20 0.54
PRSS1 P07477 1/20 0.54
CTSG P08311 1/20 0.54
CTRB1 P17538 1/20 0.54
CMA1 P23946 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
RECQL P46063 1/20 0.53
NAAA Q02083 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305562 0.92 GAA (0.65) LMNAPOLBHPGDGAASMN1; SMN2
Hydrochloric Acid SCHEMBL6421806 0.90 GAA (0.63) LMNAPOLBHPGDGAASMN1; SMN2
Benzoic Acid SCHEMBL3096844 0.87 GAA (0.59) LMNAPOLBHPGDGAASMN1; SMN2
SCHEMBL620074 0.86 POLB (0.66) LMNAPOLBHPGDALDH1A1KMT2A
SCHEMBL6716169 0.85 NPC1 (0.66) LMNAPOLBHPGDSMN1; SMN2KMT2A
SCHEMBL1245952 0.84 CYP1A2 (0.64) LMNAPOLBHPGDALDH1A1GAA
SCHEMBL17226037 0.84 NAAA (0.65) LMNAPOLBHPGDALDH1A1GAA
SCHEMBL6657326 0.84 HDAC2 (0.65) LMNAPOLBHPGDALDH1A1GAA
SCHEMBL28856675 0.84 LMNA (0.63) LMNAPOLBHPGDALDH1A1GAA
SCHEMBL23471096 0.82 POLB (0.58) LMNAPOLBHPGDALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10252291-B2 Photo-curing of thermoplastic coatings COLOPLAST A/S (DK) 2019-04-09 US disclosed
EP-2394676-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2018-03-28 EP disclosed
CN-103468108-B Coating composition COLOPLAST A/S (DK) 2016-03-02 CN disclosed
EP-2459242-B1 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST AS (DK) 2015-10-21 EP disclosed
EP-2104523-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2015-08-26 EP disclosed
US-8932662-B2 Coatings prepared from poly(ethylene oxide) and photo-initator-containing scaffolds COLOPLAST A/S (DK) 2015-01-13 US disclosed
EP-2049172-B1 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST AS (DK) 2014-12-31 EP disclosed
US-20140363562-A1 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST A/S (DK) 2014-12-11 US disclosed
CN-103131315-A Coating composition COLOPLAST AS 2013-06-05 CN disclosed
US-20130115466-A1 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST A/S (DK) 2013-05-09 US disclosed
EP-2459242-A2 A MEDICAL DEVICE OF POLYOLEFIN Coloplast A/S (DK) 2012-06-06 EP disclosed
US-20120121919-A1 MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2012-05-17 US disclosed
WO-2011012137-A2 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2011-02-03 WO disclosed
US-20100119833-A1 PHOTO-CURING OF THERMOPLASTIC COATINGS MADSEN NIELS JORGEN 2010-05-13 US disclosed
US-20100049146-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2010-02-25 US disclosed
EP-2104523-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS Coloplast A/S (DK) 2009-09-30 EP disclosed
EP-2049172-A2 PHOTO-CURING OF THERMOPLASTIC COATINGS Coloplast A/S (DK) 2009-04-22 EP disclosed
WO-2008071796-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2008-06-19 WO disclosed
WO-2008012325-A2 PHOTO-CURING OF THERMOPLASTIC COATINGS COLOPLAST A/S (DK) 2008-01-31 WO disclosed