SCHEMBL770454

SCHEMBL770454

C=CCC(O)(CC=C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
TSHR P16473 2/20 0.43
HTT P42858 1/20 0.36
LMNA P02545 1/20 0.33
MAPT P10636 2/20 0.31
ABCC4 O15439 1/20 0.31
TET2 Q6N021 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycolic Acid SCHEMBL10706558 0.91 ALDH1A1 (0.48) ALDH1A1TSHRHTTLMNAMAPT
SCHEMBL6680060 0.87 ALDH1A1 (0.39) ALDH1A1TSHRHTT
SCHEMBL5703515 0.85 ALDH1A1 (0.38) ALDH1A1TSHRHTTLMNAMAPT
SCHEMBL27625780 0.85 ALDH1A1 (0.38) ALDH1A1TSHRHTT
SCHEMBL909920 0.85 ALDH1A1 (0.61) ALDH1A1TSHRLMNAMAPTKMT2A
SCHEMBL19555034 0.82 ALDH1A1 (0.39) ALDH1A1TSHRHTTLMNAMAPT
SCHEMBL21802019 0.79 KMT2A (0.39) ALDH1A1TSHRHTTMAPTKMT2A
SCHEMBL7644387 0.79 ALDH1A1 (0.37) ALDH1A1TSHR
SCHEMBL10608081 0.78
SCHEMBL27593689 0.78 ALDH1A1 (0.43) ALDH1A1TSHRHTTLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7268253-B2 Process for preparing α, α-dialkyl-α-hydroxymethyl-carboxylic acid derivatives CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2007-09-11 US claimed
EP-1666447-B1 Process for the preparation of alpha, alpha-dialkyl, alpha-hydroxymethyl-carboxylic acid derivatives CONSORTIUM ELEKTROCHEM IND (DE) 2007-02-14 EP claimed
US-20060122424-A1 Process for preparing alpha, alpha-dialkyl-alpha-hydroxymethyl-carboxylic acid derivatives CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (US) 2006-06-08 US claimed
US-4751120-A CROSSLINKED POLYESTER COATING TOYO SEIKAN KAISHA, LTD. (JP) 1988-06-14 US claimed
EP-0114080-B1 POLYMERIZABLE LIQUID COMPOSITION ADAPTED TO PRODUCE POLYMERS HAVING OUTSTANDING OPTICAL AND MECHANICAL PROPERTIES, POLYMERS AND ARTICLES OBTAINED WITH SAID COMPOSITION ENICHEM SYNTHESIS S.p.A. (IT) 1988-03-30 EP claimed
US-4687689-A CROSSLINKING TOYO SEIKAN KAISHA, LTD. (JP) 1987-08-18 US claimed
EP-0114080-A1 Polymerizable liquid composition adapted to produce polymers having outstanding optical and mechanical properties, polymers and articles obtained with said composition ENICHEM SYNTHESIS S.p.A. (IT) 1984-07-25 EP claimed
JP-10204158-A None JP disclosed
JP-60031529-A None JP disclosed
JP-2258790-A None JP disclosed
EP-2282991-B1 METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES SANOFI AVENTIS DEUTSCHLAND (DE) 2018-01-24 EP disclosed
US-20160213891-A1 Medical Dilation Element ZAMORE, ALAN 2016-07-28 US disclosed
US-9333278-B2 Medical dilation element Medtech Capital Ventures LLC (US) 2016-05-10 US disclosed
US-4687689-A CROSSLINKING TOYO SEIKAN KAISHA, LTD. (JP) 1987-08-18 US disclosed
JP-S6031529-A MODIFIED POLYSTYRENE RESIN COMPOSITION OR MOLDING NISSIN ELECTRIC CO LTD 1985-02-18 JP disclosed
US-4383903-A POLYFUNCTIONAL AROMATIC CYANATE, ACRYLIC COMPOUND, POLYFUNCTIONAL MALEIMIDE, PHOTOINITIATOR MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-05-17 US disclosed
US-4297099-A BY PENETRATION AND CROSSLINKING DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed
US-4001368-A CURING DAI NIPPON TORYO CO., LTD. (JA) 1977-01-04 US disclosed
US-3968316-A Process for the surface treatment of unsaturated rubber NIPPON ZEON CO., LTD. (JA) 1976-07-06 US disclosed
JP-S0631529-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122424-A1 Process for preparing alpha, alpha-dialkyl-alpha-hydroxymethyl-carboxylic acid derivatives DDC, ADH1C, MCCC2 ALDH1A1 32/4885TSHR 4475/4885HTT 1432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.