SCHEMBL1246034

SCHEMBL1246034

O=Cc1c(Cl)ccc2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.60
CYP2A6 P11509 4/20 0.54
TDP1 Q9NUW8 3/20 0.52
ALDH1A1 P00352 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
CYP1A2 P05177 3/20 0.50
MAPT P10636 3/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
NPC1 O15118 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GAA P10253 2/20 0.46
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44
PAX8 Q06710 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3707056 0.90 HPRT1 (0.52) ERN1CYP2A6TDP1ALDH1A1MEN1
SCHEMBL3767140 0.90 HPRT1 (0.52) ERN1CYP2A6TDP1ALDH1A1MEN1
SCHEMBL3694889 0.82 ALDH1A1 (0.47) ERN1CYP2A6TDP1ALDH1A1MEN1
SCHEMBL3777795 0.81 ALDH1A1 (0.45) ERN1CYP2A6TDP1ALDH1A1MEN1
SCHEMBL3697087 0.81 ALDH1A1 (0.45) ERN1CYP2A6TDP1ALDH1A1MEN1
SCHEMBL6413858 0.79 CYP2A6 (0.54) ERN1CYP2A6TDP1ALDH1A1MEN1
SCHEMBL5495492 0.79 CYP2A6 (0.54) ERN1CYP2A6TDP1ALDH1A1MEN1
SCHEMBL808500 0.78 ERN1 (0.64) ERN1CYP2A6TDP1ALDH1A1MEN1
SCHEMBL29391032 0.78 ERN1 (0.64) ERN1CYP2A6TDP1ALDH1A1MEN1
SCHEMBL10488359 0.78 CYP2A6 (0.44) ERN1CYP2A6TDP1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3743061-A1 CANNABINOIDS AND DERIVATIVES FOR PROMOTING IMMUNOGENICITY OF TUMOR AND INFECTED CELLS Pascal Biosciences Inc. (CA) 2020-12-02 EP claimed
WO-2019144126-A1 CANNABINOIDS AND DERIVATIVES FOR PROMOTING IMMUNOGENICITY OF TUMOR AND INFECTED CELLS PASCAL BIOSCIENCES INC. (CA) 2019-07-25 WO claimed
US-12519071-B2 Structure containing Sn layer or Sn alloy layer ISHIHARA CHEMICAL CO., LTD. (JP) 2026-01-06 US disclosed
EP-3238861-B1 SOLDER MATERIAL, SOLDER PASTE, FOAM SOLDER, FLUX COATING MATERIAL SENJU METAL INDUSTRY CO (JP) 2025-08-27 EP disclosed
US-12388035-B2 Structure comprising under barrier metal and solder layer, and method for producing structure ISHIHARA CHEMICAL CO., LTD. (JP) 2025-08-12 US disclosed
WO-2025033019-A1 COMPOUND, COMPOSITION, METHOD FOR EXPRESSING SENSITIZING EFFECT, AND PRODUCTION METHOD 三菱瓦斯化学株式会社 2025-02-13 WO disclosed
WO-2024214321-A1 COMPOUND, COMPOSITION, METHOD FOR EXPRESSING SENSITIZING EFFECT, AND METHOD FOR PRODUCING SAME 三菱瓦斯化学株式会社 2024-10-17 WO disclosed
US-20240258255-A1 STRUCTURE COMPRISING UNDER BARRIER METAL AND SOLDER LAYER, AND METHOD FOR PRODUCING STRUCTURE ISHIHARA CHEMICAL CO., LTD. (JP) 2024-08-01 US disclosed
EP-4350748-A1 STRUCTURE COMPRISING UNDER BARRIER METAL AND SOLDER LAYER, AND METHOD FOR PRODUCING STRUCTURE Ishihara Chemical Co., Ltd (JP) 2024-04-10 EP disclosed
US-11939691-B2 Tin or tin alloy electroplating bath, and electronic component having electrodeposit formed thereon using the plating bath ISHIHARA CHEMICAL CO., LTD. (JP) 2024-03-26 US disclosed
CN-117501421-A Structure containing underlying barrier metal and solder layer 石原化学株式会社 2024-02-02 CN disclosed
EP-0180897-A2 5-Fluorouracil derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-14 EP disclosed
EP-0180188-A2 A composition for increasing the anti-cancer activity of an anti-cancer compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-05-07 EP disclosed
US-4582576-A LEAD OR TIN SALT A SULFONIC ACID, SURFACTANT, AND BRIGHTENERS MCGEAN-ROHCO, INC. (US) 1986-04-15 US disclosed
US-4448971-A Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones PFIZER INC. (US) 1984-05-15 US disclosed
EP-0039795-B1 PROCESS FOR THE PREPARATION OF 1,2-BENZISOTHIAZOLES BASF Aktiengesellschaft (DE) 1983-10-12 EP disclosed
US-4407811-A Hypoglycemic 5-substituted oxazolidine-2,4-diones PFIZER INC. (US) 1983-10-04 US disclosed
US-4399296-A TRIMETHYLSILYL CYANOHYDRIN INTERMEDIATES PFIZER INC. (US) 1983-08-16 US disclosed
US-4367234-A HYPOGLYCEMIC AGENTS PFIZER INC. (US) 1983-01-04 US disclosed
EP-0039795-A1 Process for the preparation of 1,2-benzisothiazoles BASF Aktiengesellschaft (DE) 1981-11-18 EP disclosed