Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657946 | 0.91 | ALOX5 (0.44) | ALOX5PTGER2TBXA2RPTGFRALDH1A1 | |
| SCHEMBL657947 | 0.91 | ALOX5 (0.44) | ALOX5PTGER2TBXA2RPTGFRALDH1A1 | |
| SCHEMBL1114571 | 0.85 | ALOX5 (0.38) | ALOX5PTGER2TBXA2RPTGFRALDH1A1 | |
| SCHEMBL658527 | 0.81 | ALOX5 (0.40) | ALOX5PTGER2TBXA2RPTGFRALDH1A1 | |
| SCHEMBL658528 | 0.81 | ALOX5 (0.39) | ALOX5PTGER2TBXA2RPTGFRALDH1A1 | |
| SCHEMBL2030946 | 0.81 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL2030947 | 0.81 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL1981267 | 0.79 | ALOX5 (0.48) | ALOX5PTGER2TBXA2RPTGFRALDH1A1 | |
| SCHEMBL1114460 | 0.79 | ALOX5 (0.48) | ALOX5PTGER2TBXA2RPTGFRALDH1A1 | |
| SCHEMBL12557161 | 0.79 | ALOX5 (0.48) | ALOX5PTGER2TBXA2RPTGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889894-B2 | Compounds for use in therapy | BANGOR UNIVERSITY (GB) | 2014-11-18 | — | — | US | disclosed |
| US-8728515-B2 | Adjuvants for use in vaccination | BANGOR UNIVERSITY (GB) | 2014-05-20 | — | — | US | disclosed |
| US-20110150981-A1 | Compounds for Use in Therapy | BANGOR UNIVERSITY (GB) | 2011-06-23 | — | — | US | disclosed |
| US-20110142916-A1 | Adjuvants for Use in Vaccination | BANGOR UNIVERSITY (GB) | 2011-06-16 | — | — | US | disclosed |
| EP-2278995-A2 | COMPOUNDS FOR USE IN THERAPY | Bangor University (GB) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009130506-A2 | COMPOUNDS FOR USE IN THERAPY | BANGOR UNIVERSITY (GB) | 2009-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110142916-A1 | Adjuvants for Use in Vaccination | NR1H3, NR1H2, INTS6 | ALOX5 663/4885PTGER2 3030/4885TBXA2R 1770/4885 |
| US-20110150981-A1 | Compounds for Use in Therapy | CD4, MSR1, TST | ALOX5 186/4885PTGER2 2624/4885TBXA2R 887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.