SCHEMBL2030946

SCHEMBL2030946

CCCCCCCCCCCCCCCCCCCCCCCC[C@@H](C(=O)O)[C@@H](CCCCCCCCCCCCCCC[C@@H]1C[C@@H]1CCCCCCCCCCCCCCCCCC[C@H](OC1CCCCO1)[C@@H](C)CCCCCCCCCCCCCCCCCC)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2030944 1.00 ALOX5 (0.32) ALOX5
SCHEMBL2030947 1.00 ALOX5 (0.32) ALOX5
SCHEMBL1114498 0.87 ALOX5 (0.35) ALOX5
SCHEMBL1978800 0.87 ALOX5 (0.35) ALOX5
SCHEMBL657946 0.85 ALOX5 (0.44) ALOX5
SCHEMBL657947 0.85 ALOX5 (0.44) ALOX5
SCHEMBL1114571 0.83 ALOX5 (0.38) ALOX5
SCHEMBL1246039 0.81 ALOX5 (0.39) ALOX5
SCHEMBL9457010 0.81 MEN1 (0.32)
SCHEMBL9457333 0.76 FFAR4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8889894-B2 Compounds for use in therapy BANGOR UNIVERSITY (GB) 2014-11-18 US disclosed
EP-2620158-A1 Adjuvants for use in vaccination Bangor University (GB) 2013-07-31 EP disclosed
US-20110150981-A1 Compounds for Use in Therapy BANGOR UNIVERSITY (GB) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110150981-A1 Compounds for Use in Therapy CD4, MSR1, TST ALOX5 186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.